Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 6/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | POLA1 | P09884 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | OXER1 | Q8TDS5 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8852310 | 0.96 | TSHR (0.65) | ALDH1A1LMNATSHRPOLBPOLA1 | |
| SCHEMBL10925756 | 0.86 | TSHR (0.62) | ALDH1A1LMNATSHRPOLBPOLA1 | |
| SCHEMBL14400928 | 0.83 | TSHR (0.46) | ALDH1A1LMNATSHRPOLBPOLA1 | |
| SCHEMBL21127357 | 0.81 | TSHR (0.45) | ALDH1A1LMNATSHRPOLBPOLA1 | |
| SCHEMBL14975 | 0.81 | TSHR (0.88) | ALDH1A1LMNATSHRRECQLKMT2A | |
| SCHEMBL6557587 | 0.81 | ALDH1A1 (0.50) | ALDH1A1LMNATSHRSMN1; SMN2 | |
| SCHEMBL27953228 | 0.81 | TSHR (0.88) | ALDH1A1LMNATSHRRECQLKMT2A | |
| SCHEMBL28036724 | 0.79 | LMNA (0.58) | ALDH1A1LMNATSHRPOLBPOLA1 | |
| Ethylene SCHEMBL11220450 | 0.79 | TSHR (0.74) | ALDH1A1LMNATSHRPOLBPOLA1 | |
| Ethylene SCHEMBL11226694 | 0.79 | TSHR (0.74) | ALDH1A1LMNATSHRPOLBPOLA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7276622-B2 | Method for producing oxygen-containing compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-10-02 | — | — | US | disclosed |
| US-20060173221-A1 | Method for producing oxygen-containing compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2006-08-03 | — | — | US | disclosed |
| EP-1609777-A1 | METHOD FOR PRODUCING OXYGEN-CONTAINING COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2005-12-28 | — | — | EP | disclosed |
| US-6965029-B2 | Method for producing enantiomer-free 6,8 dihydroxy octanoic acid esters by means of asymmetric, catalytic hydrogenation | VIATRIS GMBH & CO. KG (DE) | 2005-11-15 | — | — | US | disclosed |
| EP-1303475-B1 | METHOD FOR PRODUCING ENANTIOMER-FREE 6,8 DIHYDROXY OCTANOIC ACID ESTERS BY MEANS OF ASYMMETRIC, CATALYTIC HYDROGENATION | VIATRIS GMBH (DE) | 2005-06-08 | — | — | EP | disclosed |
| US-20040030178-A1 | Method for producing enantiomer-free 6,8 dihydroxy octanoic acid esters by means of asymmetric, catalytic hydrogenation | VIATRIS GMBH & CO. KG (DE) | 2004-02-12 | — | — | US | disclosed |
| EP-1303475-A1 | METHOD FOR PRODUCING ENANTIOMER-FREE 6,8 DIHYDROXY OCTANOIC ACID ESTERS BY MEANS OF ASYMMETRIC, CATALYTIC HYDROGENATION | VIATRIS GmbH & Co. KG (DE) | 2003-04-23 | — | — | EP | disclosed |
| WO-2002010113-A1 | METHOD FOR PRODUCING ENANTIOMER-FREE 6,8 DIHYDROXY OCTANOIC ACID ESTERS BY MEANS OF ASYMMETRIC, CATALYTIC HYDROGENATION | VIATRIS GMBH & CO. KG (DE) | 2002-02-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060173221-A1 | Method for producing oxygen-containing compound | GPX4, DUOX2, SCO2 | ALDH1A1 863/4885LMNA 4036/4885TSHR 4390/4885 |
| US-20040030178-A1 | Method for producing enantiomer-free 6,8 dihydroxy octanoic acid esters by means of asymmetric, catalytic hydrogenation | ACSL6, HACL2, CYP8B1 | ALDH1A1 180/4885LMNA 2721/4885TSHR 3479/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.