SCHEMBL28972541

SCHEMBL28972541

CC(C)(C)c1cc(-c2ccccc2)cc(C(C)(C)C)c1I

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.43
CA1 P00915 1/20 0.43
ALDH1A1 P00352 2/20 0.39
CYP2C9 P11712 2/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2C19 P33261 1/20 0.38
TSHR P16473 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
CRHBP P24387 1/20 0.34
CRHR2 Q13324 1/20 0.34
RXRA P19793 3/20 0.33
RXRB P28702 3/20 0.33
KIF11 P52732 2/20 0.33
KDM4E B2RXH2 1/20 0.33
HTT P42858 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
SLC22A2 O15244 1/20 0.33
SLC22A1 O15245 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27338803 0.88 CA1 (0.38) CA2CA1ALDH1A1CYP2C9CYP1A2
SCHEMBL20306786 0.79 RXRA (0.39) CA2CA1ALDH1A1CYP2C9TSHR
SCHEMBL28678059 0.78 KIF11 (0.46) ALDH1A1TSHRMEN1KMT2ARXRA
SCHEMBL426214 0.78 CA2 (0.74) CA2CA1ALDH1A1CYP2C9CYP1A2
SCHEMBL28500388 0.78 CA1 (0.43) CA2CA1ALDH1A1CYP2C9CYP1A2
Benzene SCHEMBL29148570 0.78 CA2 (0.74) CA2CA1ALDH1A1CYP2C9CYP1A2
SCHEMBL13840641 0.77 CA2 (0.71) CA2CA1ALDH1A1CYP2C9CYP1A2
SCHEMBL27991629 0.76 RXRA (0.42) CA2CA1ALDH1A1CYP2C9TSHR
SCHEMBL4572747 0.74 CA2 (0.39) CA2CA1ALDH1A1CYP2C9CYP1A2
SCHEMBL364394 0.74 CA1 (0.39) CA2CA1ALDH1A1CYP2C9CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115835754-A Organic electroluminescent device 三星显示有限公司 2023-03-21 CN disclosed