SCHEMBL28972737

SCHEMBL28972737

CCOC(=O)OC(=O)C(CC)(CC)OCC

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SOAT1 P35610 1/20 0.54
ALDH1A1 P00352 3/20 0.46
PKM P14618 2/20 0.35
KDM4E B2RXH2 1/20 0.35
LMNA P02545 2/20 0.34
HSD17B10 Q99714 1/20 0.34
CYP4F2 P78329 3/20 0.34
CYP4A11 Q02928 3/20 0.34
THRB P10828 1/20 0.34
ALOX15 P16050 1/20 0.33
MGAM O43451 1/20 0.33
GAA P10253 1/20 0.33
SI P14410 1/20 0.33
MGAM2 Q2M2H8 1/20 0.33
HTT P42858 1/20 0.33
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
TRPA1 O75762 1/20 0.31
MAPT P10636 1/20 0.31
ATM Q13315 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24780286 0.85 SOAT1 (0.35) SOAT1ALDH1A1LMNAHSD17B10CYP4F2
SCHEMBL27793139 0.83 CYP4F2 (0.42) SOAT1ALDH1A1PKMKDM4ELMNA
SCHEMBL27452723 0.77 SOAT1 (0.61) SOAT1ALDH1A1PKMKDM4ELMNA
SCHEMBL13776376 0.74 DGAT1 (0.33) ALDH1A1PKMKDM4ECYP4F2CYP4A11
SCHEMBL8370831 0.74 SOAT1 (0.64) SOAT1ALDH1A1PKMKDM4ELMNA
SCHEMBL3258251 0.73 SOAT1 (0.36) SOAT1ALDH1A1LMNAHSD17B10THRB
SCHEMBL27738039 0.72 SOAT1 (0.61) SOAT1ALDH1A1PKMKDM4ELMNA
Diethyl Pyrocarbonate SCHEMBL30366210 0.72 SOAT1 (1.00) SOAT1ALDH1A1PKMKDM4ELMNA
Diethyl Pyrocarbonate SCHEMBL15582 0.72 SOAT1 (1.00) SOAT1ALDH1A1PKMKDM4ELMNA
SCHEMBL10757809 0.72 SOAT1 (0.54) SOAT1ALDH1A1PKMKDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115677491-A Preparation process of ethyl 4- (ethoxycarbonyl) methoxybutyrate 武汉市振邦生物科技有限公司 2023-02-03 CN disclosed