Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.57 |
| ▸ | FGFR4 | P22455 | 5/20 | 0.55 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.51 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.51 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.42 |
| ▸ | GSK3B | P49841 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30206869 | 0.77 | HDAC6 (0.67) | HDAC6HDAC1HDAC2HDAC8FGFR4 | |
| SCHEMBL28972832 | 0.77 | HDAC6 (0.67) | HDAC6HDAC1HDAC2HDAC8FGFR4 | |
| SCHEMBL28116979 | 0.76 | JAK2 (0.59) | HDAC6HDAC1HDAC2HDAC8 | |
| SCHEMBL30206946 | 0.76 | HDAC6 (0.82) | HDAC6HDAC1HDAC2HDAC8FGFR4 | |
| SCHEMBL28258654 | 0.73 | TRPA1 (0.41) | GSK3B | |
| SCHEMBL28533750 | 0.72 | FGFR4 (0.79) | HDAC6HDAC1HDAC2HDAC8FGFR4 | |
| SCHEMBL30206816 | 0.72 | FGFR4 (0.79) | HDAC6HDAC1HDAC2HDAC8FGFR4 | |
| SCHEMBL4494131 | 0.72 | HDAC6 (0.71) | HDAC6HDAC1HDAC2HDAC8FGFR4 | |
| SCHEMBL4494397 | 0.72 | HDAC6 (0.73) | HDAC6HDAC1HDAC2HDAC8FGFR4 | |
| SCHEMBL26393577 | 0.72 | FADS1 (0.47) | HDAC6HDAC1HDAC2HDAC8FGFR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112521336-B | Indazole and pyrrolopyridine compounds and application thereof | 温州医科大学 | 2023-03-28 | — | — | CN | disclosed |