Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 7/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 4/20 | 0.37 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.36 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.36 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL91462 | 0.78 | DYRK1A (0.40) | DYRK1AMAP2K4GSK3B | |
| SCHEMBL11754096 | 0.77 | TRPA1 (0.50) | TRPA1MAPK10MAP2K4 | |
| SCHEMBL28079409 | 0.76 | TRPA1 (0.49) | TRPA1MAPK10MAP2K4 | |
| Hydrochloric Acid SCHEMBL8487463 | 0.76 | TRPA1 (0.49) | TRPA1MAPK10MAP2K4 | |
| SCHEMBL11755947 | 0.73 | JAK2 (0.54) | DYRK1A | |
| SCHEMBL28972793 | 0.73 | HDAC6 (0.60) | GSK3B | |
| SCHEMBL25200397 | 0.72 | PDPK1 (0.53) | DYRK1AMAPK10MAPK14GSK3B | |
| SCHEMBL11748390 | 0.72 | FADS1 (0.54) | TRPA1MAP2K4GSK3BKCNQ3KCNQ2 | |
| SCHEMBL11748510 | 0.69 | NTRK1 (0.43) | MAPK10GSK3B | |
| SCHEMBL26393980 | 0.69 | GSK3B (0.57) | DYRK1AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109121414-A | Benzopyrazole compounds and analogs thereof | 拜奥克里斯特制药公司 | 2019-01-01 | — | — | CN | disclosed |