Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.32 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 3/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12488116 | 0.80 | ALDH1A1 (0.36) | PTGDR2PTGDRSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL30280774 | 0.75 | KDM4E (0.37) | SMN1; SMN2ALDH1A1MAPTALOX5APFEN1 | |
| SCHEMBL19559130 | 0.72 | MAPT (0.34) | PTGDR2PTGDRSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL18432260 | 0.70 | PDK2 (0.37) | PTGDR2PTGDRSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL30280880 | 0.70 | PTGER4 (0.41) | ALDH1A1MAPTALOX5APFEN1LMNA | |
| SCHEMBL12489103 | 0.69 | CAMKK2 (0.36) | PTGDR2PTGDRALDH1A1MAPTHTR2A | |
| SCHEMBL12489172 | 0.69 | CFTR (0.36) | PTGDR2PTGDRSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL31312362 | 0.68 | FASN (0.42) | ALDH1A1MAPTGAA | |
| SCHEMBL12488856 | 0.68 | FASN (0.42) | ALDH1A1MAPTGAA | |
| SCHEMBL12488878 | 0.68 | GAA (0.42) | SMN1; SMN2ALDH1A1MAPTLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116139138-A | Heterocyclic modulators of lipid synthesis | 3-V生物科学股份有限公司 | 2023-05-23 | — | — | CN | disclosed |
| CN-110177551-B | Heterocyclic modulators of lipid synthesis | 3-V生物科学股份有限公司 | 2023-02-17 | — | — | CN | disclosed |