Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | HTR5A | P47898 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.34 |
| ▸ | FEN1 | P39748 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30280880 | 0.84 | PTGER4 (0.41) | KDM4EPTGER4ALDH1A1ALOX5APFEN1 | |
| SCHEMBL28974087 | 0.81 | KDM4E (0.38) | KDM4EPTGER4ALDH1A1DRD2DRD4 | |
| SCHEMBL30281099 | 0.79 | DRD2 (0.45) | KDM4EALDH1A1DRD2DRD4DRD3 | |
| SCHEMBL30281122 | 0.78 | PTGER4 (0.43) | KDM4EPTGER4ALDH1A1PDK2PDK4 | |
| SCHEMBL30281075 | 0.78 | ALDH1A1 (0.39) | KDM4EALDH1A1DRD2DRD4DRD3 | |
| SCHEMBL30280992 | 0.76 | PTGER4 (0.43) | KDM4EPTGER4ALDH1A1ALOX5APFEN1 | |
| SCHEMBL28974071 | 0.75 | PTGDR2 (0.32) | ALDH1A1ALOX5APFEN1GAAMAPT | |
| SCHEMBL12488116 | 0.75 | ALDH1A1 (0.36) | KDM4EALDH1A1PDK2PDK4GAA | |
| SCHEMBL28974014 | 0.75 | PDK2 (0.40) | KDM4EPTGER4ALDH1A1DRD2DRD4 | |
| SCHEMBL8583580 | 0.74 | KDM4E (0.37) | KDM4EALDH1A1DRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116139138-A | Heterocyclic modulators of lipid synthesis | 3-V生物科学股份有限公司 | 2023-05-23 | — | — | CN | disclosed |
| CN-110177551-B | Heterocyclic modulators of lipid synthesis | 3-V生物科学股份有限公司 | 2023-02-17 | — | — | CN | disclosed |