SCHEMBL28974098

SCHEMBL28974098

CC1C[CH]C(C(C)C)CC1.[MgH2]

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.31
TRPM8 Q7Z2W7 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3422050 0.98 TRPA1 (0.32) TRPA1TRPM8
SCHEMBL20358052 0.98 TRPA1 (0.32) TRPA1TRPM8
SCHEMBL521672 0.98 TRPA1 (0.32) TRPA1TRPM8
SCHEMBL522463 0.98 TRPA1 (0.32) TRPA1TRPM8
SCHEMBL43485 0.98 TRPA1 (0.32) TRPA1TRPM8
SCHEMBL3422054 0.98 TRPA1 (0.32) TRPA1TRPM8
SCHEMBL4622479 0.98 TRPA1 (0.32) TRPA1TRPM8
SCHEMBL27943781 0.95 TRPA1 (0.31) TRPA1TRPM8
SCHEMBL27943902 0.89
Dimethyl Sulfoxide SCHEMBL7538397 0.87

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107954824-B Method for synthesizing menthane carboxamide by using menthol 昆山亚香香料股份有限公司 2022-12-27 CN claimed
CN-111393293-B Ester ammonolysis reaction catalyst composition and preparation method of L-menthane carboxamide 万华化学集团股份有限公司 2022-09-20 CN claimed
CN-107954824-B Method for synthesizing menthane carboxamide by using menthol 昆山亚香香料股份有限公司 2022-12-27 CN disclosed
CN-107954824-B Method for synthesizing menthane carboxamide by using menthol 昆山亚香香料股份有限公司 2022-12-27 CN disclosed
CN-111393293-B Ester ammonolysis reaction catalyst composition and preparation method of L-menthane carboxamide 万华化学集团股份有限公司 2022-09-20 CN disclosed