Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3422050 | 1.00 | TRPA1 (0.32) | TRPA1TRPM8 | |
| SCHEMBL20358052 | 1.00 | TRPA1 (0.32) | TRPA1TRPM8 | |
| SCHEMBL4622479 | 1.00 | TRPA1 (0.32) | TRPA1TRPM8 | |
| SCHEMBL3422054 | 1.00 | TRPA1 (0.32) | TRPA1TRPM8 | |
| SCHEMBL43485 | 1.00 | TRPA1 (0.32) | TRPA1TRPM8 | |
| SCHEMBL521672 | 1.00 | TRPA1 (0.32) | TRPA1TRPM8 | |
| Dimethyl Sulfoxide SCHEMBL7538397 | 0.89 | — | — | |
| SCHEMBL283746 | 0.74 | — | — | |
| SCHEMBL14109264 | 0.69 | — | — | |
| SCHEMBL8479861 | 0.68 | SIGMAR1 (0.41) | TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2181980-A1 | A process for the preparation of (R)-1-aminoindanes | Chemo Ibérica, S.A. (ES) | 2010-05-05 | — | — | EP | claimed |
| US-20060211603-A1 | Ramoplanin derivatives possessing antibacterial activity | VICURON PHARMACEUTICALS INC. (US) | 2006-09-21 | — | — | US | claimed |
| US-6730788-B1 | COUPLING WITH KETONE IN PRESENCE OF LANTHANIDE II METAL COMPOUND | UNIVERSITY OF NOTRE DAME | 2004-05-04 | — | — | US | claimed |
| US-6713650-B2 | ELEVATES ATP BINDING CASSETTE TRANSPORTER 1 EXPRESSION THEREBY INCREASING EFFLUX OF CHOLESTEROL FROM CELLS BY ACTIVE TRANSFER INTO HIGH DENSITY LIPOPROTEINS | CV THERAPEUTICS, INC. | 2004-03-30 | — | — | US | claimed |
| EP-1377283-A2 | COMPOUNDS OF THE FORMULA R1-X-Y-Z-NR2R3 AS ABCA-1 ELEVATING AGENTS AGAINST CORONARY ARTERY DISEASE OR ATHEROSCLEROSIS | CV THERAPEUTICS, INC. (US) | 2004-01-07 | — | — | EP | claimed |
| WO-2003103651-A1 | COMPOUNDS OF THE FORMU;A R1-X-Y-Z-NR2R3 AS ABCA-1 ELEVATING AGENTS AGAINST CAD OR ATHEROSCLEROSIS | CV THERAPEUTICS, INC. (US) | 2003-12-18 | — | — | WO | claimed |
| US-20020082257-A1 | ABCA-1 Elevating compounds | CV THERAPEUTICS, INC. | 2002-06-27 | — | — | US | claimed |
| WO-2002046141-A2 | COUMPOUNDS OF THE FORMULA R1-X-Y-Z-NR2R3 AS ABCA-1 ELEVATING AGENTS AGAINST CORONARY ARTERY DISEASE OR ATHEROSCLEROSIS | CV THERAPEUTICS, INC. (US) | 2002-06-13 | — | — | WO | claimed |
| WO-2024149389-A1 | SUBSTITUTED BRIDGE RING INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 苏州泽璟生物制药股份有限公司 | 2024-07-18 | — | — | WO | disclosed |
| US-20240101532-A1 | HETEROARYL CARBOXAMIDE COMPOUND | KOTOBUKI PHARMACEUTICAL CO., LTD. (JP) | 2024-03-28 | — | — | US | disclosed |
| US-20240043403-A1 | HETEROARYL CARBOXAMIDE COMPOUND | ASTELLAS PHARMA INC. (JP) | 2024-02-08 | — | — | US | disclosed |
| US-10544177-B2 | Chiral dihydrobenzooxaphosphole ligands and synthesis thereof | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2020-01-28 | — | — | US | disclosed |
| EP-3551638-A2 | NOVEL CHIRAL DIHYDROBENZOOXAPHOSPHOLE LIGANDS AND SYNTHESIS THEREOF | Boehringer Ingelheim International GmbH (DE) | 2019-10-16 | — | — | EP | disclosed |
| US-10421769-B2 | Anticancer property studies of chiral palladium N-heterocyclic carbene complexes and process for preparation thereof | India Institute of Technology Bombay (IN) | 2019-09-24 | — | — | US | disclosed |
| US-20120029202-A1 | Process for the Preparation of 5-Substituted 3-Aryl-3-(trifluoromethyl)-3,4-dihydro-2H-pyrroles | BAYER CROPSCIENCE AG (DE) | 2012-02-02 | — | — | US | disclosed |
| EP-2181980-A1 | A process for the preparation of (R)-1-aminoindanes | Chemo Ibérica, S.A. (ES) | 2010-05-05 | — | — | EP | disclosed |
| US-20070244153-A1 | Diamine Derivative, Process of Preparation Thereof, and Fungicide Comprising Diamine Derivative as an Active Ingredient | MITSUI CHEMICALS, INC. (JP) | 2007-10-18 | — | — | US | disclosed |
| EP-1770085-A1 | DIAMINE DERIVATIVE, PROCESS FOR PRODUCING THE SAME AND FUNGICIDE CONTAINING THE DERIVATIVE AS ACTIVE INGREDIENT | Mitsui Chemicals, Inc. (JP) | 2007-04-04 | — | — | EP | disclosed |
| US-20060211603-A1 | Ramoplanin derivatives possessing antibacterial activity | VICURON PHARMACEUTICALS INC. (US) | 2006-09-21 | — | — | US | disclosed |
| US-5212173-A | Gastrointestinal | KALI-CHEMIE PHARMA GMBH (DE) | 1993-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10421769-B2 | Anticancer property studies of chiral palladium N-heterocyclic carbene complexes and process for preparation thereof | PDCD1LG2, PDCD1, ODC1 | TRPA1 4344/4885TRPM8 3089/4885 |
| US-20070244153-A1 | Diamine Derivative, Process of Preparation Thereof, and Fungicide Comprising Diamine Derivative as an Active Ingredient | DDT, AOC1, QDPR | TRPA1 1133/4885TRPM8 4025/4885 |
| US-20240101532-A1 | HETEROARYL CARBOXAMIDE COMPOUND | PDCD1, DGKA, CD274 | TRPA1 2187/4885TRPM8 1917/4885 |
| US-20240043403-A1 | HETEROARYL CARBOXAMIDE COMPOUND | PDCD1, DGKA, CD274 | TRPA1 2187/4885TRPM8 1917/4885 |
| US-20120029202-A1 | Process for the Preparation of 5-Substituted 3-Aryl-3-(trifluoromethyl)-3,4-dihydro-2H-pyrroles | CYP4F3, PAH, IDH3B | TRPA1 2660/4885TRPM8 4536/4885 |
| US-20060211603-A1 | Ramoplanin derivatives possessing antibacterial activity | CLSPN, LMAN2, RPN2 | TRPA1 2822/4885TRPM8 2307/4885 |
| US-20020082257-A1 | ABCA-1 Elevating compounds | ABCD3, ABCE1, ABCB4 | TRPA1 4425/4885TRPM8 3147/4885 |
| US-10544177-B2 | Chiral dihydrobenzooxaphosphole ligands and synthesis thereof | DCPS, PNPO, PPIP5K2 | TRPA1 994/4885TRPM8 1091/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.