Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3422050 | 1.00 | TRPA1 (0.32) | TRPA1TRPM8 | |
| SCHEMBL20358052 | 1.00 | TRPA1 (0.32) | TRPA1TRPM8 | |
| SCHEMBL522463 | 1.00 | TRPA1 (0.32) | TRPA1TRPM8 | |
| SCHEMBL4622479 | 1.00 | TRPA1 (0.32) | TRPA1TRPM8 | |
| SCHEMBL3422054 | 1.00 | TRPA1 (0.32) | TRPA1TRPM8 | |
| SCHEMBL43485 | 1.00 | TRPA1 (0.32) | TRPA1TRPM8 | |
| Dimethyl Sulfoxide SCHEMBL7538397 | 0.89 | — | — | |
| SCHEMBL283746 | 0.74 | — | — | |
| SCHEMBL14109264 | 0.69 | — | — | |
| SCHEMBL8479861 | 0.68 | SIGMAR1 (0.41) | TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 186 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11091424-B2 | Preparation of acetate compounds via a ketene compound | BASF SE (DE) | 2021-08-17 | — | — | US | claimed |
| CN-108218847-B | Aryloxy phenoxy alkanoic acid derivative and medical application thereof | 三峡大学 | 2021-03-23 | — | — | CN | claimed |
| EP-3728179-A1 | PREPARATION OF ACETATE COMPOUNDS VIA A KETENE COMPOUND | BASF SE (DE) | 2020-10-28 | — | — | EP | claimed |
| US-20200308094-A1 | PREPARATION OF ACETATE COMPOUNDS VIA A KETENE COMPOUND | BASF SE (DE) | 2020-10-01 | — | — | US | claimed |
| EP-3168215-B1 | PROCESS FOR PREPARATION OF BARNIDIPINE | USV PRIVATE LTD (IN) | 2020-05-20 | — | — | EP | claimed |
| EP-3168215-A2 | PROCESS FOR PREPARATION OF BARNIDIPINE | USV Private Limited (IN) | 2017-05-17 | — | — | EP | claimed |
| EP-1501514-B1 | PROTEIN KINASE MODULATORS AND METHODS OF USE | EXELIXIS INC (US) | 2012-12-19 | — | — | EP | claimed |
| EP-2292591-A2 | Process for the preparation of cyclopropyl derivatives | AstraZeneca AB (SE) | 2011-03-09 | — | — | EP | claimed |
| EP-2181980-A1 | A process for the preparation of (R)-1-aminoindanes | Chemo Ibérica, S.A. (ES) | 2010-05-05 | — | — | EP | claimed |
| US-20100041757-A1 | N-ARYL-HYDROXYALKYLIDENE-CARBOXAMIDE COMPOUNDS AND THEIR USE | WEI EDWARD TAK | 2010-02-18 | — | — | US | claimed |
| US-20080118558-A1 | N-Arylshydroxyalkylidene carboxamide compositions and methods | WEI EDWARD T | 2008-05-22 | — | — | US | claimed |
| US-20070155755-A1 | N-arylshydroxyalkylidene-carboxamide compositions and methods | WEI EDWARD T | 2007-07-05 | — | — | US | claimed |
| US-20070053834-A1 | Radioligands for the TRP-M8 receptor and methods therewith | WEI EDWARD T | 2007-03-08 | — | — | US | claimed |
| EP-1760066-A2 | Processes for the preparation of cyclopropyl carboxylic acid derivatives and intermediates provided by these processes | AstraZeneca AB (SE) | 2007-03-07 | — | — | EP | claimed |
| US-20060258879-A1 | Process for the preparation of cyclopropyl carboxylic acid esters and derivatives | ASTRAZENECA AB (SE) | 2006-11-16 | — | — | US | claimed |
| US-20060211603-A1 | Ramoplanin derivatives possessing antibacterial activity | VICURON PHARMACEUTICALS INC. (US) | 2006-09-21 | — | — | US | claimed |
| US-20050187211-A1 | N-arylsalkyl-carboxamide compositions and methods | WEI EDWARD T (US) | 2005-08-25 | — | — | US | claimed |
| US-20040171881-A1 | N,N'-substituted-1,3-diamino-2-hydroxypropane derivatives | PHARMACIA & UPJOHN COMPANY | 2004-09-02 | — | — | US | claimed |
| US-20030120105-A1 | Process for the preparation of cyclopropyl carboxylic acid esters and derivatives | ASTRAZENECA AB (SE) | 2003-06-26 | — | — | US | claimed |
| US-4331605-A | Lactone ring containing sulfonic acid esters | ROUSSEL UCLAF (FR) | 1982-05-25 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060258879-A1 | Process for the preparation of cyclopropyl carboxylic acid esters and derivatives | MCCC2, DHPS, CYP3A4 | TRPA1 4397/4885TRPM8 3856/4885 |
| US-20050187211-A1 | N-arylsalkyl-carboxamide compositions and methods | OPRL1, TRPV1, TRPA1 | TRPA1 3/4885TRPM8 13/4885 |
| US-20030120105-A1 | Process for the preparation of cyclopropyl carboxylic acid esters and derivatives | MCCC2, DHPS, CYP3A4 | TRPA1 4397/4885TRPM8 3856/4885 |
| US-20080118558-A1 | N-Arylshydroxyalkylidene carboxamide compositions and methods | TRPV1, OPRL1, HRH2 | TRPA1 6/4885TRPM8 41/4885 |
| US-20200308094-A1 | PREPARATION OF ACETATE COMPOUNDS VIA A KETENE COMPOUND | AKR1C2, KAT8, KAT5 | TRPA1 2710/4885TRPM8 2859/4885 |
| US-11091424-B2 | Preparation of acetate compounds via a ketene compound | AKR1C2, KAT8, KAT5 | TRPA1 2710/4885TRPM8 2859/4885 |
| US-20070053834-A1 | Radioligands for the TRP-M8 receptor and methods therewith | GPR68, TRPM8, OPRL1 | TRPA1 8/4885TRPM8 2/4885 |
| US-20070155755-A1 | N-arylshydroxyalkylidene-carboxamide compositions and methods | TRPV1, OPRL1, HRH2 | TRPA1 5/4885TRPM8 38/4885 |
| US-20040171881-A1 | N,N'-substituted-1,3-diamino-2-hydroxypropane derivatives | BACE1, BACE2, PSEN1 | TRPA1 4750/4885TRPM8 3856/4885 |
| US-20100041757-A1 | N-ARYL-HYDROXYALKYLIDENE-CARBOXAMIDE COMPOUNDS AND THEIR USE | TRPV1, TRPA1, TRPV2 | TRPA1 2/4885TRPM8 15/4885 |
| US-20060211603-A1 | Ramoplanin derivatives possessing antibacterial activity | CLSPN, LMAN2, RPN2 | TRPA1 2822/4885TRPM8 2307/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.