Tetrahydrofuran

Tetrahydrofuran

SCHEMBL28974153

C1CCOC1.Cc1cc(Br)ccc1Cc1ccc(OCc2ccccc2)cc1

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PTGES O14684 1/20 0.43
MAOB P27338 7/20 0.43
MAOA P21397 2/20 0.41
AR P10275 1/20 0.41
FFAR1 O14842 1/20 0.40
FFAR4 Q5NUL3 1/20 0.40
S1PR1 P21453 1/20 0.40
S1PR5 Q9H228 1/20 0.40
CCR5 P51681 2/20 0.40
MRGPRX4 Q96LA9 1/20 0.40
PKM P14618 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
NPC1 O15118 1/20 0.40
CASP3 P42574 1/20 0.40
RAB9A P51151 1/20 0.40
SENP8 Q96LD8 1/20 0.40
SENP7 Q9BQF6 1/20 0.40
SENP6 Q9GZR1 1/20 0.40
TDP1 Q9NUW8 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30039160 0.91 MAOB (0.51) PTGESMAOBCCR5
SCHEMBL23040922 0.91 MAOB (0.51) PTGESMAOBCCR5
Tetrahydrofuran SCHEMBL29117380 0.81 MRGPRX4 (0.52) MAOBMAOAARFFAR1FFAR4
SCHEMBL1009096 0.80 MAOB (0.51) PTGESMAOBCCR5RAB9A
SCHEMBL21218509 0.76 LMNA (0.55) MAOBMAOAL3MBTL1RAB9A
SCHEMBL14966760 0.76 MAOB (0.49) MAOBL3MBTL1NPC1RAB9ATDP1
SCHEMBL1010163 0.73 MAOB (0.51) PTGESMAOBCCR5
SCHEMBL29816877 0.73 MAOB (0.51) PTGESMAOBCCR5
SCHEMBL11839266 0.72 APP (0.62) MAOBMAOAARFFAR1FFAR4
Tetrahydrofuran SCHEMBL28032446 0.72 KMT2A (0.51) MAOBMAOAFFAR1FFAR4L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110066302-B Glucopyranosyl derivative and use thereof 广东东阳光药业有限公司 2022-12-27 CN disclosed