Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.66 |
| ▸ | GAA | P10253 | 2/20 | 0.66 |
| ▸ | GFER | P55789 | 1/20 | 0.66 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.57 |
| ▸ | RAD52 | P43351 | 1/20 | 0.55 |
| ▸ | PEPD | P12955 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.52 |
| ▸ | MITF | O75030 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | KIF11 | P52732 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL230957 | 0.92 | MDM2 (0.67) | MAPTGAAGFERMDM2PEPD | |
| Hydrochloric Acid SCHEMBL27714679 | 0.90 | MDM2 (0.64) | MAPTGAAGFERMDM2PEPD | |
| SCHEMBL4630961 | 0.84 | KIF11 (0.63) | MAPTGAAGFERPOLBMDM2 | |
| SCHEMBL23999548 | 0.83 | MDM2 (0.83) | MAPTGAAPOLBMDM2RAD52 | |
| SCHEMBL10836457 | 0.80 | POLB (0.60) | MAPTGAAPOLBMDM2RAD52 | |
| SCHEMBL5062623 | 0.80 | PEPD (0.80) | MAPTGAAGFERPEPDALDH1A1 | |
| SCHEMBL5008975 | 0.79 | HSD17B10 (0.58) | PEPDALDH1A1NPC1 | |
| SCHEMBL30832865 | 0.79 | MAPT (1.00) | MAPTGAAGFERPOLBPEPD | |
| SCHEMBL30828552 | 0.78 | KDM4E (0.85) | MAPTGAAPOLBNPC1KDM4E | |
| SCHEMBL23999623 | 0.78 | KDM4E (0.85) | MAPTGAAPOLBNPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115867562-A | AKT3 modulators | 乔治穆内有限责任公司 | 2023-03-28 | — | — | CN | disclosed |