P-Xylene

P-Xylene

SCHEMBL28974549

CN1CCN(N)CC1.Cc1ccc(C)cc1

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 1/20 0.44
HRH4 Q9H3N8 3/20 0.42
KMT2A Q03164 4/20 0.42
MEN1 O00255 2/20 0.41
ACHE P22303 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
KDM4E B2RXH2 1/20 0.40
ALDH1A1 P00352 1/20 0.40
GAA P10253 1/20 0.40
MAPT P10636 1/20 0.40
ADRA2C P18825 1/20 0.40
GFER P55789 1/20 0.40
PTK2B Q14289 1/20 0.40
ESR2 Q92731 1/20 0.40
HTR6 P50406 1/20 0.39
SCN1A P35498 1/20 0.38
SCN2A Q99250 1/20 0.38
SCN3A Q9NY46 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Toluene SCHEMBL28974702 0.89 LMNA (0.48) OPRM1HRH4ACHEADRA2C
O-Xylene SCHEMBL28974550 0.81 TSHR (0.46) OPRM1HRH4KMT2AMEN1ACHE
SCHEMBL65054 0.81
SCHEMBL7004904 0.81
Hydrochloric Acid SCHEMBL1700097 0.78 GNAI3 (0.42) KMT2ATDP1KDM4EALDH1A1GAA
Hydrochloric Acid SCHEMBL9523475 0.78
Hydrochloric Acid SCHEMBL8080295 0.75 GNAI3 (0.41) KMT2ATDP1KDM4EALDH1A1GAA
SCHEMBL81814 0.73 MAPT (0.65) KMT2AMEN1KDM4EALDH1A1GAA
SCHEMBL15489560 0.73 MAPT (0.65) KMT2AMEN1KDM4EALDH1A1GAA
SCHEMBL21574870 0.71 GAA (0.52) HRH4KMT2AMEN1KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115703750-A Extraction and purification method of 1-amino-4-methylpiperazine 黑龙江华瑞生物科技有限公司 2023-02-17 CN disclosed