Toluene

Toluene

SCHEMBL28974702

CN1CCN(N)CC1.Cc1ccccc1

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.48
TSHR P16473 1/20 0.48
ALOX12 P18054 1/20 0.48
ACHE P22303 1/20 0.48
MC4R P32245 2/20 0.44
DRD1 P21728 2/20 0.44
DRD3 P35462 2/20 0.44
OPRM1 P35372 2/20 0.44
CHRM2 P08172 1/20 0.44
CHRM4 P08173 1/20 0.44
CHRM5 P08912 1/20 0.44
ADRA2A P08913 1/20 0.44
ADORA3 P0DMS8 1/20 0.44
CYP2D6 P10635 1/20 0.44
CHRM1 P11229 1/20 0.44
CHRM3 P20309 1/20 0.44
ADRA1D P25100 1/20 0.44
HTR2A P28223 1/20 0.44
HTR2C P28335 1/20 0.44
HRH1 P35367 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
P-Xylene SCHEMBL28974549 0.89 OPRM1 (0.44) ACHEOPRM1ADRA2CHRH4
O-Xylene SCHEMBL28974550 0.84 TSHR (0.46) TSHRACHEMC4RDRD1DRD3
Toluene SCHEMBL1459338 0.79 LMNA (0.55) LMNATSHRALOX12ACHEMC4R
Toluene SCHEMBL28205212 0.78 ADRB1 (0.50) LMNATSHRALOX12ACHECYP2D6
Ethylbenzene SCHEMBL28974651 0.78 TP53 (0.54) MC4RCHRM4CHRM5CHRM1HRH4
SCHEMBL65054 0.75
SCHEMBL7004904 0.75
Toluene SCHEMBL17164584 0.74 LMNA (0.48) LMNATSHRALOX12ACHEPOLB
Methylpiperazine SCHEMBL27759929 0.74 ADRB1 (0.50) LMNATSHRALOX12ACHECYP2D6
Hydrochloric Acid SCHEMBL9523475 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115703750-B Extraction and purification method of 1-amino-4-methylpiperazine 黑龙江华瑞生物科技有限公司 2024-07-02 CN disclosed
CN-115703750-A Extraction and purification method of 1-amino-4-methylpiperazine 黑龙江华瑞生物科技有限公司 2023-02-17 CN disclosed