Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | F11 | P03951 | 9/20 | 0.53 |
| ▸ | CTSS | P25774 | 4/20 | 0.53 |
| ▸ | CTSK | P43235 | 3/20 | 0.53 |
| ▸ | CTSB | P07858 | 2/20 | 0.53 |
| ▸ | CTSL | P07711 | 1/20 | 0.53 |
| ▸ | PYGL | P06737 | 3/20 | 0.52 |
| ▸ | ACE | P12821 | 1/20 | 0.48 |
| ▸ | AKT1 | P31749 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28974589 | 1.00 | HDAC8 (0.54) | HDAC8F11CTSSCTSKCTSB | |
| SCHEMBL28602428 | 0.92 | F11 (0.55) | HDAC8F11CTSSCTSK | |
| SCHEMBL28919287 | 0.92 | F11 (0.55) | HDAC8F11CTSSCTSK | |
| SCHEMBL23466599 | 0.90 | MMP13 (0.55) | HDAC8F11CTSSCTSKCTSB | |
| SCHEMBL23466603 | 0.90 | MMP13 (0.55) | HDAC8F11CTSSCTSKCTSB | |
| SCHEMBL29758100 | 0.90 | MMP13 (0.55) | HDAC8F11CTSSCTSKCTSB | |
| SCHEMBL28673878 | 0.88 | KLK7 (0.46) | HDAC8F11CTSS | |
| SCHEMBL28673880 | 0.88 | KLK7 (0.46) | HDAC8F11CTSS | |
| SCHEMBL28692985 | 0.88 | F11 (0.45) | HDAC8F11CTSSCTSKCTSB | |
| SCHEMBL28692986 | 0.88 | F11 (0.45) | HDAC8F11CTSSCTSKCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114728917-A | Oxamide derivative, preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2022-07-08 | — | — | CN | disclosed |