Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 2/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | CTSS | P25774 | 4/20 | 0.48 |
| ▸ | CTSK | P43235 | 3/20 | 0.48 |
| ▸ | CTSB | P07858 | 2/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | PYGL | P06737 | 3/20 | 0.48 |
| ▸ | F11 | P03951 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ACE | P12821 | 1/20 | 0.45 |
| ▸ | REN | P00797 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23466599 | 1.00 | MMP13 (0.55) | MMP13HDAC8CTSSCTSKCTSB | |
| SCHEMBL23466603 | 1.00 | MMP13 (0.55) | MMP13HDAC8CTSSCTSKCTSB | |
| SCHEMBL28941305 | 0.93 | F11 (0.51) | MMP13HDAC8MMP2PYGLF11 | |
| SCHEMBL28941304 | 0.93 | F11 (0.51) | MMP13HDAC8MMP2PYGLF11 | |
| SCHEMBL28746481 | 0.92 | MMP13 (0.53) | MMP13HDAC8CTSSCTSKMMP2 | |
| SCHEMBL28292652 | 0.92 | MMP13 (0.53) | MMP13HDAC8CTSSCTSKMMP2 | |
| SCHEMBL28746480 | 0.92 | MMP13 (0.53) | MMP13HDAC8CTSSCTSKMMP2 | |
| SCHEMBL28974587 | 0.90 | HDAC8 (0.54) | HDAC8CTSSCTSKCTSBCTSL | |
| SCHEMBL28974589 | 0.90 | HDAC8 (0.54) | HDAC8CTSSCTSKCTSBCTSL | |
| SCHEMBL28746506 | 0.90 | MMP13 (0.52) | MMP13HDAC8CTSSCTSKMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114728917-A | Oxamide derivative, preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2022-07-08 | — | — | CN | disclosed |