Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 5/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | CDC7 | O00311 | 3/20 | 0.58 |
| ▸ | DBF4 | Q9UBU7 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL290675 | 0.90 | KDM4E (0.62) | TRPM8KDM4EALDH1A1CDC7DBF4 | |
| SCHEMBL2885887 | 0.89 | TRPM8 (0.78) | TRPM8KDM4EALDH1A1CDC7DBF4 | |
| SCHEMBL289325 | 0.89 | TRPM8 (0.65) | TRPM8KDM4EALDH1A1CDC7DBF4 | |
| SCHEMBL290306 | 0.88 | ALDH1A1 (0.59) | TRPM8KDM4EALDH1A1CDC7DBF4 | |
| SCHEMBL289156 | 0.88 | ALDH1A1 (0.65) | TRPM8KDM4EALDH1A1CDC7DBF4 | |
| SCHEMBL289583 | 0.87 | KDM4E (0.65) | TRPM8KDM4EALDH1A1CDC7DBF4 | |
| SCHEMBL290101 | 0.86 | ALDH1A1 (0.64) | TRPM8KDM4EALDH1A1CDC7DBF4 | |
| SCHEMBL289730 | 0.86 | CDC7 (0.79) | KDM4EALDH1A1CDC7DBF4LMNA | |
| SCHEMBL289893 | 0.86 | KDM4E (0.55) | TRPM8KDM4EALDH1A1CDC7DBF4 | |
| Hydrochloric Acid SCHEMBL289729 | 0.85 | CDC7 (0.77) | KDM4EALDH1A1CDC7DBF4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427447-A2 | SMALL MOLECULE INHIBITORS OF INFLUENZA A AND B VIRUS AND RESPIRATORY SYNCYTIAL VIRUS REPLICATION | Pike Pharma GmbH (CH) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010128163-A2 | SMALL MOLECULE INHIBITORS OF INFLUENZA A AND B VIRUS AND RESPIRATORY SYNCYTIAL VIRUS REPLICATION | PIKE PHARMA GMBH (CH) | 2010-11-11 | — | — | WO | disclosed |