Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | CDC7 | O00311 | 2/20 | 0.58 |
| ▸ | DBF4 | Q9UBU7 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | CASP3 | P42574 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.56 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL290675 | 0.90 | KDM4E (0.62) | ALDH1A1KDM4ECDC7DBF4MAPT | |
| SCHEMBL2085303 | 0.89 | CDC7 (0.73) | ALDH1A1KDM4ECDC7DBF4MAPT | |
| SCHEMBL290050 | 0.89 | ALDH1A1 (0.58) | ALDH1A1KDM4ECDC7DBF4MAPT | |
| SCHEMBL289893 | 0.89 | KDM4E (0.55) | ALDH1A1KDM4ECDC7DBF4MAPT | |
| SCHEMBL289746 | 0.88 | TRPM8 (0.62) | ALDH1A1KDM4ECDC7DBF4MAPT | |
| SCHEMBL289156 | 0.88 | ALDH1A1 (0.65) | ALDH1A1KDM4ECDC7DBF4MAPT | |
| SCHEMBL289730 | 0.86 | CDC7 (0.79) | ALDH1A1KDM4ECDC7DBF4LMNA | |
| SCHEMBL290101 | 0.86 | ALDH1A1 (0.64) | ALDH1A1KDM4ECDC7DBF4MAPT | |
| SCHEMBL289848 | 0.86 | KDM4E (0.55) | ALDH1A1KDM4ECDC7DBF4MAPT | |
| Hydrochloric Acid SCHEMBL289729 | 0.85 | CDC7 (0.77) | ALDH1A1KDM4ECDC7DBF4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427447-A2 | SMALL MOLECULE INHIBITORS OF INFLUENZA A AND B VIRUS AND RESPIRATORY SYNCYTIAL VIRUS REPLICATION | Pike Pharma GmbH (CH) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010128163-A2 | SMALL MOLECULE INHIBITORS OF INFLUENZA A AND B VIRUS AND RESPIRATORY SYNCYTIAL VIRUS REPLICATION | PIKE PHARMA GMBH (CH) | 2010-11-11 | — | — | WO | disclosed |