Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 2/20 | 0.40 |
| ▸ | RXRB | P28702 | 2/20 | 0.40 |
| ▸ | RXRG | P48443 | 2/20 | 0.40 |
| ▸ | GLS | O94925 | 3/20 | 0.40 |
| ▸ | SDCBP | O00560 | 1/20 | 0.39 |
| ▸ | SDC2 | P34741 | 1/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | ATR | Q13535 | 1/20 | 0.38 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25497278 | 0.86 | HDAC1 (0.47) | HDAC1NAMPTGLSCTSSCTSK | |
| SCHEMBL26328902 | 0.85 | MAPT (0.42) | HDAC1NAMPTL3MBTL1LMNAAKT1 | |
| SCHEMBL26328906 | 0.84 | NAMPT (0.41) | HDAC1EPHX2NR1H4NAMPTL3MBTL1 | |
| SCHEMBL30736827 | 0.83 | HDAC1 (0.58) | HDAC1EPHX2NR1H4NAMPTL3MBTL1 | |
| SCHEMBL25439945 | 0.82 | NAMPT (0.41) | HDAC1NAMPTL3MBTL1HDAC6ATR | |
| SCHEMBL26329031 | 0.82 | DYRK1A (0.44) | EPHX2NR1H4L3MBTL1LMNATSHR | |
| SCHEMBL1244728 | 0.81 | EPHX2 (0.56) | HDAC1EPHX2NR1H4NAMPTL3MBTL1 | |
| SCHEMBL25367309 | 0.81 | NAMPT (0.47) | HDAC1NAMPTL3MBTL1GLSSDCBP | |
| SCHEMBL15322811 | 0.80 | NAMPT (0.50) | HDAC1NAMPTL3MBTL1SDCBPSDC2 | |
| SCHEMBL13977598 | 0.78 | KDM4E (0.49) | NAMPTL3MBTL1LMNAGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115873014-B | Controllable proteolytic targeted chimera and application thereof | 中国药科大学 | 2024-08-20 | — | — | CN | disclosed |
| CN-115991880-B | Dendrimer PAMAM-G5-TCO and preparation method and application thereof | 中国药科大学 | 2024-03-19 | — | — | CN | disclosed |
| CN-115991880-A | Dendrimer PAMAM-G5-TCO and preparation method and application thereof | 中国药科大学 | 2023-04-21 | — | — | CN | disclosed |
| CN-115873014-A | Controllable proteolysis targeting chimera and application thereof | 中国药科大学 | 2023-03-31 | — | — | CN | disclosed |