Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ATR | Q13535 | 1/20 | 0.42 |
| ▸ | SDCBP | O00560 | 1/20 | 0.41 |
| ▸ | SDC2 | P34741 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HPN | P05981 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | GLS | O94925 | 1/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30392217 | 0.85 | NAMPT (0.43) | NAMPTL3MBTL1HDAC1HDAC6GRM2 | |
| SCHEMBL15322811 | 0.85 | NAMPT (0.50) | NAMPTL3MBTL1HDAC1HDAC6GRM2 | |
| SCHEMBL25440112 | 0.82 | NAMPT (0.51) | NAMPTL3MBTL1HDAC1HDAC6GAA | |
| SCHEMBL16616006 | 0.82 | NAMPT (0.53) | NAMPTL3MBTL1HDAC1HDAC6GRM2 | |
| SCHEMBL25440138 | 0.81 | NAMPT (0.47) | NAMPTL3MBTL1HDAC1HDAC6GRM2 | |
| SCHEMBL26148065 | 0.81 | L3MBTL1 (0.53) | NAMPTL3MBTL1HDAC1GAASDCBP | |
| SCHEMBL26054956 | 0.81 | NAMPT (0.47) | NAMPTL3MBTL1HDAC1HDAC6GRM2 | |
| SCHEMBL28975596 | 0.81 | HDAC1 (0.46) | NAMPTL3MBTL1HDAC1HDAC6GRM2 | |
| SCHEMBL22746024 | 0.80 | ITGA4 (0.53) | — | |
| SCHEMBL26328902 | 0.80 | MAPT (0.42) | NAMPTL3MBTL1HDAC1AKT1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4314031-A1 | MASKED IL12 PROTEIN | Tagworks Pharmaceuticals B.V. (NL) | 2024-02-07 | — | — | EP | disclosed |
| WO-2023158305-A1 | MASKED IL12 PROTEIN | TAGWORKS PHARMACEUTICALS B.V. (NL) | 2023-08-24 | — | — | WO | disclosed |