Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.40 |
| ▸ | KDM4A | O75164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | BCL2 | P10415 | 1/20 | 0.38 |
| ▸ | BECN1 | Q14457 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | ATR | Q13535 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25439945 | 0.88 | NAMPT (0.41) | NAMPTHDAC1KDM4AL3MBTL1CYP1A2 | |
| SCHEMBL26328902 | 0.88 | MAPT (0.42) | NAMPTHDAC1KDM4AL3MBTL1CYP1A2 | |
| SCHEMBL25497278 | 0.86 | HDAC1 (0.47) | NAMPTHDAC1KDM4ACYP1A2CA12 | |
| SCHEMBL26329031 | 0.86 | DYRK1A (0.44) | L3MBTL1EPHX2NR1H4ADORA3KDM4E | |
| SCHEMBL28975596 | 0.84 | HDAC1 (0.46) | NAMPTHDAC1CYP17A1L3MBTL1EPHX2 | |
| SCHEMBL13977598 | 0.81 | KDM4E (0.49) | NAMPTKDM4AL3MBTL1CYP1A2CA12 | |
| SCHEMBL26328914 | 0.80 | ADORA2A (0.39) | NAMPTHDAC1KDM4AL3MBTL1CYP1A2 | |
| SCHEMBL8127981 | 0.79 | EPHX2 (0.59) | NAMPTHDAC1KDM4AL3MBTL1EPHX2 | |
| SCHEMBL25367309 | 0.79 | NAMPT (0.47) | NAMPTHDAC1CYP17A1L3MBTL1HDAC6 | |
| SCHEMBL25440112 | 0.78 | NAMPT (0.51) | NAMPTHDAC1L3MBTL1EPHX2NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11767302-B2 | Reagents and methods for tetrazine synthesis | UNIVERSITY OF DELAWARE (US) | 2023-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11767302-B2 | Reagents and methods for tetrazine synthesis | TST, CYP4F8, CYP4Z1 | NAMPT 1678/4885HDAC1 1927/4885CYP17A1 404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.