Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITK | Q08881 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | BTK | Q06187 | 6/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20082945 | 0.88 | NPC1 (0.43) | ITKNPC1RAB9AMEN1KMT2A | |
| SCHEMBL19017644 | 0.85 | ALDH1A1 (0.43) | MEN1KMT2AALDH1A1KDM4EGAA | |
| SCHEMBL27299791 | 0.81 | ALDH1A1 (0.38) | MEN1KMT2AALDH1A1KDM4EGAA | |
| SCHEMBL20400198 | 0.79 | BTK (0.38) | ITKNPC1RAB9AMEN1KMT2A | |
| SCHEMBL20400199 | 0.79 | BTK (0.38) | ITKNPC1RAB9AMEN1KMT2A | |
| SCHEMBL20629916 | 0.79 | ITK (0.37) | ITKNPC1RAB9AMEN1KMT2A | |
| SCHEMBL20240590 | 0.78 | BTK (0.41) | ITKNPC1RAB9AMEN1KMT2A | |
| SCHEMBL20629865 | 0.78 | MAPT (0.38) | ITKNPC1RAB9AMEN1KMT2A | |
| SCHEMBL15710719 | 0.78 | MAPT (0.38) | ITKNPC1RAB9AMEN1KMT2A | |
| SCHEMBL19017337 | 0.78 | ALDH1A1 (0.46) | MEN1KMT2AALDH1A1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110248949-B | Immunoproteasome inhibitors | 普林斯匹亚生物制药公司 | 2023-02-17 | — | — | CN | disclosed |