Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 3/20 | 0.43 |
| ▸ | CNR1 | P21554 | 12/20 | 0.38 |
| ▸ | CNR2 | P34972 | 12/20 | 0.38 |
| ▸ | RGS4 | P49798 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.36 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | CTSD | P07339 | 1/20 | 0.34 |
| ▸ | CTSE | P14091 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28976813 | 0.87 | LMNA (0.39) | MTORCNR1CNR2RGS4PIK3CA | |
| SCHEMBL28976862 | 0.87 | RIPK3 (0.41) | MTORCNR1CNR2RGS4PIK3CA | |
| SCHEMBL28976755 | 0.86 | RGS4 (0.44) | CNR1CNR2RGS4CTSDCTSE | |
| SCHEMBL28976869 | 0.84 | EBP (0.46) | CNR1CNR2BACE1 | |
| SCHEMBL28976895 | 0.84 | BACE1 (0.51) | CNR1CNR2RGS4HTR6CTSD | |
| SCHEMBL28976612 | 0.84 | CNR2 (0.40) | CNR1CNR2RGS4BACE1 | |
| SCHEMBL30272737 | 0.82 | CYP3A4 (0.38) | MTORCNR1CNR2RGS4PIK3CA | |
| SCHEMBL28976683 | 0.81 | CTSD (0.33) | MTORCNR1CNR2RGS4PIK3CA | |
| SCHEMBL28976611 | 0.80 | PRKDC (0.38) | MTORCNR1CNR2RGS4PIK3CA | |
| SCHEMBL28976620 | 0.80 | NOTUM (0.37) | MTORCNR1CNR2PIK3CARPTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115703761-A | Compound as WWP1 inhibitor and application thereof | 首药控股(北京)股份有限公司 | 2023-02-17 | — | — | CN | disclosed |