Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.43 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.43 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22749527 | 1.00 | THRA (0.49) | THRATHRBLIPGLTB4RLTB4R2 | |
| SCHEMBL28191406 | 0.97 | THRA (0.52) | THRATHRBLIPGLTB4RLTB4R2 | |
| SCHEMBL31278477 | 0.87 | THRA (0.49) | THRATHRBLIPGLTB4RLTB4R2 | |
| SCHEMBL1487512 | 0.87 | THRA (0.49) | THRATHRBLIPGLTB4RLTB4R2 | |
| SCHEMBL28376630 | 0.86 | THRA (0.58) | THRATHRBLIPGLTB4RLTB4R2 | |
| SCHEMBL29778064 | 0.86 | THRA (0.58) | THRATHRBLIPGLTB4RLTB4R2 | |
| SCHEMBL317708 | 0.86 | THRA (0.58) | THRATHRBLIPGLTB4RLTB4R2 | |
| SCHEMBL8433693 | 0.86 | THRA (0.58) | THRATHRBLIPGLTB4RLTB4R2 | |
| SCHEMBL8372832 | 0.86 | THRA (0.58) | THRATHRBLIPGLTB4RLTB4R2 | |
| SCHEMBL9294713 | 0.85 | LTB4R (0.48) | THRATHRBLIPGLTB4RLTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115867611-A | Polyorganosiloxane-containing polymer particles, composition, resin composition, and molded article | 三菱化学株式会社 | 2023-03-28 | — | — | CN | disclosed |