Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 7/20 | 0.70 |
| ▸ | CES1 | P23141 | 2/20 | 0.70 |
| ▸ | FABP3 | P05413 | 5/20 | 0.61 |
| ▸ | TERT | O14746 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | BLM | P54132 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | FABP4 | P15090 | 2/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.58 |
| ▸ | PPARG | P37231 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | PPARD | Q03181 | 2/20 | 0.58 |
| ▸ | PPARA | Q07869 | 2/20 | 0.58 |
| ▸ | GMNN | O75496 | 1/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2897766 | 1.00 | FAAH (0.70) | FAAHCES1FABP3TERTCYP1A2 | |
| SCHEMBL2827382 | 0.90 | FAAH (0.71) | FAAHCES1FABP3MAPTBLM | |
| SCHEMBL29794313 | 0.89 | CES1 (0.63) | FAAHCES1CYP1A2HSD17B10KMT2A | |
| SCHEMBL1334928 | 0.89 | CES1 (0.63) | FAAHCES1CYP1A2HSD17B10KMT2A | |
| SCHEMBL20600305 | 0.83 | FAAH (0.78) | FAAHFABP3TERTCYP1A2MAPT | |
| SCHEMBL15400706 | 0.83 | FAAH (0.78) | FAAHFABP3TERTCYP1A2MAPT | |
| SCHEMBL24938529 | 0.82 | FAAH (1.00) | FAAHCES1TERTCYP1A2MAPT | |
| SCHEMBL4085373 | 0.82 | FAAH (1.00) | FAAHCES1TERTCYP1A2MAPT | |
| SCHEMBL24938531 | 0.82 | FAAH (1.00) | FAAHCES1TERTCYP1A2MAPT | |
| SCHEMBL8059738 | 0.82 | FAAH (1.00) | FAAHCES1TERTCYP1A2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240085429-A1 | ALTERING PROTEIN FUNCTION BY PHARMACOLOGICAL TARGETING OF MEMBRANE DOMAINS | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2024-03-14 | — | — | US | disclosed |
| US-10156566-B2 | Detoxification of microbial virulence factors in oral cavity | THE PROCTER & GAMBLE COMPANY (US) | 2018-12-18 | — | — | US | disclosed |
| EP-3292215-A1 | DETOXIFICATION OF MICROBIAL VIRULENCE FACTORS IN ORAL CAVITY | The Procter and Gamble Company (US) | 2018-03-14 | — | — | EP | disclosed |
| US-20170119643-A1 | DETOXIFICATION OF MICROBIAL VIRULENCE FACTORS IN ORAL CAVITY | THE PROCTER & GAMBLE COMPANY | 2017-05-04 | — | — | US | disclosed |
| WO-2016179561-A1 | DETOXIFICATION OF MICROBIAL VIRULENCE FACTORS IN ORAL CAVITY | THE PROCTER & GAMBLE COMPANY (US) | 2016-11-10 | — | — | WO | disclosed |
| US-8263558-B2 | Methods of preparation of recombinant forms of human beta-amyloid protein and uses of these proteins | ABBOTT LABORATORIES (US) | 2012-09-11 | — | — | US | disclosed |
| EP-1370867-B1 | PROTEIN PROFILING PLATFORM | ACTIVX BIOSCIENCES INC (US) | 2010-08-04 | — | — | EP | disclosed |
| US-20090214515-A1 | METHODS OF PREPARATION OF RECOMBINANT FORMS OF HUMAN BETA-AMYLOID PROTEIN AND USES OF THESE PROTEINS | ABBVIE DEUTSCHLAND GMBH & CO KG (DE) | 2009-08-27 | — | — | US | disclosed |
| EP-1963363-A2 | METHODS OF PREPARATION OF RECOMBINANT FORMS OF HUMAN BETA-AMYLOID PROTEIN AND USES OF THESE PROTEINS | Abbott Laboratories (US) | 2008-09-03 | — | — | EP | disclosed |
| EP-1572311-A4 | ASSAY FOR DETERMINING THE ACTIVITY OF FATTY ACID AMIDE HYDROLASE | JANSSEN PHARMACEUTICA NV (BE) | 2007-12-12 | — | — | EP | disclosed |
| EP-1370867-A1 | PROTEIN PROFILING PLATFORM | Activx Biosciences, Inc. (US) | 2003-12-17 | — | — | EP | disclosed |
| EP-1275006-A2 | PROTEOMIC ANALYSIS USING ACTIVITY-BASED PROBE LIBRARIES | The Scripps Research Institute (US) | 2003-01-15 | — | — | EP | disclosed |
| US-20020182652-A1 | Proteomic analysis | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2002-12-05 | — | — | US | disclosed |
| US-20020182651-A1 | Protein profiling platform | ACTIVX BIOSCIENCES, INC. | 2002-12-05 | — | — | US | disclosed |
| WO-2002071066-A1 | PROTEIN PROFILING PLATFORM | ACTIVX BIOSCIENCES, INC. (US) | 2002-09-12 | — | — | WO | disclosed |
| US-20020064799-A1 | Proteomic analysis | THE SCRIPPS RESEARCH INSTITUTE OF AN ASSIGNMENT | 2002-05-30 | — | — | US | disclosed |
| US-20020045194-A1 | Proteomic analysis | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2002-04-18 | — | — | US | disclosed |
| US-20020040275-A1 | Proteomic analysis | THE SCRIPPS RESEARCH INSTITUTE | 2002-04-04 | — | — | US | disclosed |
| WO-2001077668-A2 | PROTEOMIC ANALYSIS USING ACTIVE-SITE DIRECTED PROBES | THE SCRIPPS RESEARCH INSTITUTE (US) | 2001-10-18 | — | — | WO | disclosed |
| WO-2001077684-A2 | PROTEOMIC ANALYSIS USING ACTIVITY-BASED PROBE LIBRARIES | THE SCRIPPS RESEARCH INSTITUTE (US) | 2001-10-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170119643-A1 | DETOXIFICATION OF MICROBIAL VIRULENCE FACTORS IN ORAL CAVITY | GSTM2, GSTA2, GSTA1 | FAAH 2168/4885CES1 842/4885FABP3 1257/4885 |
| US-10156566-B2 | Detoxification of microbial virulence factors in oral cavity | GSTM2, GSTA2, GSTA1 | FAAH 2168/4885CES1 842/4885FABP3 1257/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.