SCHEMBL28977993

SCHEMBL28977993

CC(C)(C)C(=O)ON1CCC(n2cc(N)c(C(F)F)n2)CC1

nearest known ligand 0.35

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KDM5A P29375 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21997425 0.83 CTSD (0.43)
SCHEMBL28978050 0.82 KDM5A (0.33) KDM5A
SCHEMBL30267127 0.78 KDM5A (0.41) KDM5A
SCHEMBL31628491 0.77 IRAK4 (0.40)
SCHEMBL31628457 0.77 IRAK4 (0.40)
SCHEMBL31237017 0.76 PIK3CA (0.43) KDM5A
SCHEMBL25986236 0.75 KDM5A (0.34) KDM5A
SCHEMBL25694498 0.75 KDM5A (0.34) KDM5A
SCHEMBL23560092 0.75 LMNA (0.36)
SCHEMBL21997702 0.75 LMNA (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115710274-A IRAK4 degradation agent, preparation method and application thereof 上海领泰生物医药科技有限公司 2023-02-24 CN disclosed