Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21070609 | 0.84 | ALDH1A1 (0.44) | MAPTALDH1A1 | |
| SCHEMBL28977993 | 0.82 | KDM5A (0.35) | KDM5A | |
| SCHEMBL29768198 | 0.80 | KDM5A (0.38) | KDM5AMAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL31628804 | 0.79 | ALDH1A1 (0.43) | MAPTALDH1A1 | |
| SCHEMBL31205669 | 0.78 | JAK1 (0.41) | KMT2A | |
| SCHEMBL21791740 | 0.78 | ALDH1A1 (0.41) | KDM5AMAPTALDH1A1 | |
| SCHEMBL23728461 | 0.78 | ACHE (0.35) | — | |
| SCHEMBL25817050 | 0.78 | PDE4D (0.33) | KDM5AMAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL25986239 | 0.78 | PDE4D (0.33) | KDM5AMAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL25986279 | 0.78 | PDE4D (0.33) | KDM5AMAPTMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115710274-A | IRAK4 degradation agent, preparation method and application thereof | 上海领泰生物医药科技有限公司 | 2023-02-24 | — | — | CN | disclosed |