Acrylonitrile

Acrylonitrile

SCHEMBL28978

C=CC#N.CC=C(C)C(=O)O

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.43
TSHR P16473 1/20 0.43
PTGS1 P23219 1/20 0.31
AKR1C3 P42330 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylonitrile SCHEMBL1885744 1.00 ALDH1A1 (0.43) ALDH1A1TSHRPTGS1AKR1C3
Acrylonitrile SCHEMBL8743874 0.96 ALDH1A1 (0.39) ALDH1A1TSHR
Acrylonitrile SCHEMBL1655293 0.96 ALDH1A1 (0.39) ALDH1A1TSHR
Acrylic Acid SCHEMBL10979925 0.94 LMNA (0.42) ALDH1A1TSHR
Acrylonitrile SCHEMBL15546879 0.92 TDP1 (0.44) ALDH1A1TSHR
1,1-Dichloroethene SCHEMBL3442603 0.92 ALDH1A1 (0.36) ALDH1A1TSHR
Acrylonitrile SCHEMBL1813039 0.90 ALDH1A1 (0.35) ALDH1A1TSHR
Styrene SCHEMBL301613 0.82 AKR1C3 (0.49) ALDH1A1TSHRAKR1C3
Acetonitrile SCHEMBL28310850 0.82 PTGS1 (0.34) PTGS1AKR1C3
Acrylonitrile SCHEMBL388549 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 261 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4143040-A1 SPRING ASSEMBLY FOR A CHASSIS, VEHICLE CHASSIS COMPRISING A SPRING ASSEMBLY, METHOD FOR PRODUCING A SPRING ASSEMBLY FOR A VEHICLE CHASSIS AND USE OF A SPRING ASSEMBLY ThyssenKrupp Federn und Stabilisatoren GmbH (DE) 2023-03-08 EP claimed
WO-2021219522-A1 SPRING ASSEMBLY FOR A CHASSIS, VEHICLE CHASSIS COMPRISING A SPRING ASSEMBLY, METHOD FOR PRODUCING A SPRING ASSEMBLY FOR A VEHICLE CHASSIS AND USE OF A SPRING ASSEMBLY ThyssenKrupp Federn und Stabilisatoren GmbH (DE) 2021-11-04 WO claimed
EP-3092458-A1 IGNITION ELEMENT FOR IGNITING AMMUNITION Voere Holding GmbH (AT) 2016-11-16 EP claimed
US-8937166-B2 68Ga generator ITM ISOTOPEN TECHNOLOGIEN MUNCHEN AG (DE) 2015-01-20 US claimed
US-20140163211-A1 68Ga Generator ITM Isotopen Technologien München AG (DE) 2014-06-12 US claimed
EP-2439747-B1 68 Ga generator ITM ISOTOPEN TECHNOLOGIEN MUENCHEN AG (DE) 2013-09-18 EP claimed
US-8487047-B2 68Ga generator ITM ISOTOPEN TECHNOLOGIEN MUNCHEN AG (DE) 2013-07-16 US claimed
US-20120252981-A1 68Ga Generator LSI FINANCING LLC, AS ADMINISTRATIVE AGENT 2012-10-04 US claimed
EP-1796900-A1 COMPOSITE BODY MADE FROM POLYACETAL AND THERMOPLASTIC VULCANISED ELASTOMER Ticona GmbH (DE) 2007-06-20 EP claimed
WO-2006034860-A1 COMPOSITE BODY MADE FROM POLYACETAL AND THERMOPLASTIC VULCANISED ELASTOMER TICONA GMBH (DE) 2006-04-06 WO claimed
US-20020160116-A1 Method for the processing of ultra-thin polymeric films THIN FILM ELECTRONICS ASA (NO) 2002-10-31 US claimed
US-6448305-B1 Antimicrobial acrylic material MICROBAN PRODUCTS COMPANY 2002-09-10 US claimed
EP-1161466-A4 ANTIMICROBIAL ACRYLIC MATERIAL MICROBAN PRODUCTS (US) 2002-04-10 EP claimed
EP-1161466-A1 ANTIMICROBIAL ACRYLIC MATERIAL MICROBAN PRODUCTS COMPANY (US) 2001-12-12 EP claimed
US-6203708-B1 FOR REMOVING SOLUBLE ELECTROLYTES FROM AN IONISING SOLVENT MONASH UNIVERSITY (AU) 2001-03-20 US claimed
WO-2000014128-A1 ANTIMICROBIAL ACRYLIC MATERIAL MICROBAN PRODUCTS COMPANY (US) 2000-03-16 WO claimed
EP-0647160-B1 ION EXCHANGE RESIN UNIV MONASH (AU) 1998-09-02 EP claimed
EP-0265762-B1 Fibrillated fibers and articles made therefrom AMERICAN CYANAMID CO (US) 1994-01-12 EP claimed
US-5210140-A Viscosity differential; improved impact resistance; molded articles THE B. F. GOODRICH COMPANY (US) 1993-05-11 US claimed
EP-0512611-A1 Improved polyvinyl chloride blends The Geon Company (US) 1992-11-11 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120252981-A1 68Ga Generator GCG, GRPR, GDA ALDH1A1 3652/4885TSHR 481/4885PTGS1 3027/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.