Isonicotinic Acid

Isonicotinic Acid

SCHEMBL28979028

Clc1ccccn1.O=C(O)c1ccncc1

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NAPRT Q6XQN6 4/20 0.61
TDP1 Q9NUW8 1/20 0.57
KMT2A Q03164 4/20 0.50
MEN1 O00255 1/20 0.50
KDM4E B2RXH2 3/20 0.49
KDM6B O15054 1/20 0.49
KDM4A O75164 1/20 0.49
KDM5C P41229 1/20 0.49
KDM4C Q9H3R0 1/20 0.49
KDM2A Q9Y2K7 1/20 0.49
KDM3A Q9Y4C1 1/20 0.49
CYP1A2 P05177 2/20 0.46
CYP3A4 P08684 2/20 0.46
PLOD2 O00469 1/20 0.46
PLOD3 O60568 1/20 0.46
ALDH1A1 P00352 1/20 0.46
CYP2D6 P10635 1/20 0.46
CYP2C9 P11712 1/20 0.46
HPGD P15428 1/20 0.46
CYP2C19 P33261 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Chloropyridine SCHEMBL7769567 0.82 TDP1 (0.76) NAPRTTDP1KMT2AALDH1A1LMNA
Niacin SCHEMBL27969761 0.81 ALDH1A1 (0.68) NAPRTTDP1KMT2AKDM4EKDM6B
Isonicotinic Acid SCHEMBL28068524 0.81 NAPRT (0.71) NAPRTKMT2AMEN1KDM4ECYP1A2
2-Chloropyridine SCHEMBL5718309 0.81 TDP1 (0.73) NAPRTTDP1KMT2AALDH1A1LMNA
2-Chloropyridine SCHEMBL28051574 0.81 TDP1 (0.73) NAPRTTDP1KMT2AALDH1A1LMNA
2-Chloropyridine SCHEMBL7210246 0.80 TDP1 (0.80) NAPRTTDP1KMT2AMEN1KDM4E
Isonicotinic Acid SCHEMBL8358038 0.80 NAPRT (0.85) NAPRTKMT2AMEN1KDM4EKDM6B
Dipyridyl SCHEMBL6037611 0.80 KDM4E (0.69) NAPRTTDP1KMT2AMEN1KDM4E
2-Picolinic Acid SCHEMBL8068407 0.80 NAPRT (0.74) NAPRTKMT2AMEN1KDM4EKDM6B
Isonicotinic Acid SCHEMBL28210508 0.80 NAPRT (0.63) NAPRTKMT2AMEN1KDM4EKDM6B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115869923-B Oxygen absorbing material, preparation method thereof and prepared adsorption material capable of simultaneously adsorbing oxygen and organic solvent 威格科技(苏州)股份有限公司 2024-03-22 CN claimed
CN-115869923-A Oxygen absorbing material, preparation method thereof and prepared adsorbing material capable of adsorbing oxygen and organic solvent simultaneously 威格科技(苏州)股份有限公司 2023-03-31 CN claimed
CN-115869923-B Oxygen absorbing material, preparation method thereof and prepared adsorption material capable of simultaneously adsorbing oxygen and organic solvent 威格科技(苏州)股份有限公司 2024-03-22 CN disclosed
CN-115869910-A Normal-temperature granulation method for gas adsorption material particles and application thereof 威格科技(苏州)股份有限公司 2023-03-31 CN disclosed
CN-115869923-A Oxygen absorbing material, preparation method thereof and prepared adsorbing material capable of adsorbing oxygen and organic solvent simultaneously 威格科技(苏州)股份有限公司 2023-03-31 CN disclosed