Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | STAT1 | P42224 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3260876 | 0.77 | MAPT (0.46) | ALDH1A1L3MBTL1ALOX15MAPTTP53 | |
| SCHEMBL747380 | 0.77 | HIF1A (0.38) | ALDH1A1ALOX15MAPTTP53TSHR | |
| SCHEMBL8533642 | 0.76 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1ATMTDP1SRD5A2 | |
| SCHEMBL6068282 | 0.72 | CNR2 (0.51) | ALDH1A1TDP1MAPTLMNATSHR | |
| SCHEMBL11883308 | 0.71 | HIF1A (0.37) | ALDH1A1ALOX15MAPTTP53CYP3A4 | |
| SCHEMBL10933450 | 0.71 | GSTP1 (0.40) | MAPTTP53SMN1; SMN2THRB | |
| SCHEMBL810175 | 0.70 | HDAC4 (0.48) | ALDH1A1L3MBTL1ATMTDP1SRD5A2 | |
| SCHEMBL11881465 | 0.69 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1ATMTDP1SRD5A2 | |
| SCHEMBL17070213 | 0.69 | ACMSD (0.51) | ALDH1A1L3MBTL1ATMTDP1SRD5A2 | |
| Benzophenone SCHEMBL27766299 | 0.69 | ALDH1A1 (0.82) | ALDH1A1L3MBTL1ATMTDP1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263738-B1 | SUBSTITUTED BENZOYLCYCLOHEXENONES | BAYER CROPSCIENCE AG (DE) | 2007-06-27 | — | — | EP | claimed |
| US-7196229-B2 | Benzoylcyclohexenone derivatives | BASF AKTIENGESELLSCHAFT (DE) | 2007-03-27 | — | — | US | claimed |
| CN-1268615-C | Substituted benzoylcyclohexenones | BAYER AG (DE) | 2006-08-09 | — | — | CN | claimed |
| US-6969697-B2 | Substituted benzoylcyclohexenones | BAYER AKTIENGESELLSCHAFT (DE) | 2005-11-29 | — | — | US | claimed |
| US-20040235793-A1 | Benzoylcyclohexenone derivatives | BASF AKTIENGESELLSCHAFT (DE) | 2004-11-25 | — | — | US | claimed |
| US-20040002599-A1 | Substituted benzoycyclohexenones | NIHON BAYER AGROCHEM K.K. (JP) | 2004-01-01 | — | — | US | claimed |
| CN-1416422-A | Substituted benzoylcyclohexenones | BAYER AG (DE) | 2003-05-07 | — | — | CN | claimed |
| EP-1263738-A1 | SUBSTITUTED BENZOYLCYCLOHEXENONES | Bayer CropScience AG (DE) | 2002-12-11 | — | — | EP | claimed |
| WO-2001066527-A1 | SUBSTITUTED BENZOYLCYCLOHEXENONES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-09-13 | — | — | WO | claimed |
| CN-107353238-B | Substituted benzoylcyclohexan cyclohexadione compounds or its tautomer, salt, preparation method, Herbicidal combinations and application | 青岛清原化合物有限公司 | 2019-09-03 | — | — | CN | disclosed |
| CN-107353238-A | Substituted benzoylcyclohexan cyclohexadione compounds or its dynamic isomer, salt, preparation method, Herbicidal combinations and application | 青岛清原化合物有限公司 | 2017-11-17 | — | — | CN | disclosed |
| EP-1392660-B1 | SUBSTITUTED BENZOYLCYCLOHEXENONES AND THEIR USE AS HERBICIDAL AGENTS | BAYER AG (DE) | 2010-08-04 | — | — | EP | disclosed |
| US-7670991-B2 | Substituted benzoylcyclohexenones and their use as herbicidal agents | BAYER CROPSCIENCE AG (DE) | 2010-03-02 | — | — | US | disclosed |
| US-7670991-B2 | Substituted benzoylcyclohexenones and their use as herbicidal agents | BAYER CROPSCIENCE AG (DE) | 2010-03-02 | — | — | US | disclosed |
| EP-0673359-A1 | BENZOYLCYCLOHEXENONES, METHODS OF PREPARING THEM AND THEIR USE AS HERBICIDES AND PLANT-GROWTH REGULATORS | Hoechst Schering AgrEvo GmbH (DE) | 1995-09-27 | — | — | EP | disclosed |
| WO-1994013619-A1 | BENZOYLCYCLOHEXENONES, METHODS OF PREPARING THEM AND THEIR USE AS HERBICIDES AND PLANT-GROWTH REGULATORS | HOECHST SCHERING AGREVO GMBH (DE) | 1994-06-23 | — | — | WO | disclosed |
| EP-0249150-B1 | CERTAIN 3-(SUBSTITUTED THIO)-2-BENZOYL-CYCLOHEX-2-ENONES | STAUFFER CHEMICAL COMPANY (US) | 1991-05-29 | — | — | EP | disclosed |
| EP-0253124-A3 | CERTAIN SUBSTITUTED 3-(SUBSTITUTED OXY)-2-BENZOYL-CYCLOHEX-2-ENONES | STAUFFER CHEMICAL COMPANY (US) | 1988-07-06 | — | — | EP | disclosed |
| EP-0253124-A2 | Certain substituted 3-(substituted oxy)-2-benzoyl-cyclohex-2-enones | STAUFFER CHEMICAL COMPANY (US) | 1988-01-20 | — | — | EP | disclosed |
| US-3930857-A | RESIST PROCESS | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1976-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040002599-A1 | Substituted benzoycyclohexenones | CYP1B1, CYP1A1, DDT | ALDH1A1 100/4885L3MBTL1 2756/4885ATM 3466/4885 |
| US-20040235793-A1 | Benzoylcyclohexenone derivatives | CYC1, CYP1B1, CYP1A1 | ALDH1A1 389/4885L3MBTL1 605/4885ATM 3168/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.