Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 7/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 7/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 5/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7928086 | 0.71 | HPGD (0.38) | ALDH1A1KMT2AL3MBTL1MEN1TSHR | |
| SCHEMBL10192351 | 0.69 | ALDH1A1 (0.49) | ALDH1A1KMT2ALMNAL3MBTL1MEN1 | |
| SCHEMBL31112271 | 0.69 | ALDH1A1 (0.49) | ALDH1A1KMT2ALMNAL3MBTL1MEN1 | |
| Oxalic Acid SCHEMBL10837929 | 0.68 | KDM4E (0.43) | ALDH1A1KMT2ALMNAL3MBTL1MEN1 | |
| Oxalic Acid SCHEMBL10837912 | 0.68 | KDM4E (0.43) | ALDH1A1KMT2ALMNAL3MBTL1MEN1 | |
| Oxalic Acid SCHEMBL10837923 | 0.68 | KDM4E (0.43) | ALDH1A1KMT2ALMNAL3MBTL1MEN1 | |
| SCHEMBL10837918 | 0.67 | ALDH1A1 (0.41) | ALDH1A1KMT2ALMNAL3MBTL1MEN1 | |
| SCHEMBL23563034 | 0.66 | DPP4 (0.36) | KMT2AL3MBTL1MEN1TSHR | |
| SCHEMBL31112136 | 0.66 | ESR1 (0.50) | ALDH1A1KMT2ALMNAL3MBTL1MEN1 | |
| SCHEMBL14610875 | 0.66 | RAB9A (0.47) | ALDH1A1KMT2AMEN1KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427469-A1 | PROCESS FOR THE PREPARATION OF RUTHENIUM METATHESIS COMPLEX CATALYSTS | F. Hoffmann-La Roche AG (CH) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010127964-A1 | PROCESS FOR THE PREPARATION OF RUTHENIUM METATHESIS COMPLEX CATALYSTS | F. HOFFMANN-LA ROCHE AG (CH) | 2010-11-11 | — | — | WO | disclosed |