Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.40 |
| ▸ | KRAS | P01116 | 1/20 | 0.40 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.40 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.40 |
| ▸ | KCNQ4 | P56696 | 2/20 | 0.40 |
| ▸ | KCNQ5 | Q9NR82 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | RORC | P51449 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28980363 | 0.79 | DYRK1A (0.43) | DYRK1AKCNQ3KCNQ2KMT2AADORA3 | |
| SCHEMBL28980350 | 0.78 | FABP4 (0.41) | MEN1KMT2AALDH1A1RXFP1 | |
| SCHEMBL28980330 | 0.77 | MCL1 (0.43) | CYP1A2CYP2C9CYP2C19DYRK1AKRAS | |
| SCHEMBL28980321 | 0.77 | OXER1 (0.43) | DYRK1AKRASKMT2ARORCALDH1A1 | |
| SCHEMBL28980358 | 0.75 | MTNR1A (0.50) | ALDH1A1 | |
| SCHEMBL28980345 | 0.73 | DYRK1A (0.40) | DYRK1ARORCALDH1A1 | |
| SCHEMBL30371592 | 0.73 | NOTUM (0.55) | CYP1A2CYP2C19MEN1KMT2AALDH1A1 | |
| SCHEMBL10973432 | 0.73 | NOTUM (0.55) | CYP1A2CYP2C19MEN1KMT2AALDH1A1 | |
| SCHEMBL668763 | 0.72 | PIM1 (0.43) | KRASMEN1KMT2AALDH1A1KCNH2 | |
| SCHEMBL31517105 | 0.72 | KCNH2 (0.41) | KRASKCNQ3KCNQ2KCNQ4KCNQ5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115894326-B | 2, 3-Hydrogen substituted aminoindole derivative, preparation method and application thereof | 佛山大学 | 2025-02-11 | — | — | CN | disclosed |
| CN-115894326-A | 2,3-hydrogen substituted aminoindole derivative, preparation method and application thereof | 佛山科学技术学院 | 2023-04-04 | — | — | CN | disclosed |