Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 2/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | CCR2 | P41597 | 1/20 | 0.40 |
| ▸ | KRAS | P01116 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 3/20 | 0.40 |
| ▸ | PPARA | Q07869 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | IDH1 | O75874 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL668802 | 0.84 | OXER1 (0.35) | S1PR1KRASPPARDPPARAOXER1 | |
| SCHEMBL28682739 | 0.83 | KCNH2 (0.41) | PIM1PIM2CES2S1PR1KRAS | |
| SCHEMBL31517105 | 0.83 | KCNH2 (0.41) | PIM1PIM2CES2S1PR1KRAS | |
| SCHEMBL20905231 | 0.81 | KRAS (0.53) | PIM1PIM2S1PR1KRASMEN1 | |
| SCHEMBL15218078 | 0.79 | MAP2K4 (0.45) | KRASIDH1KDRKCNH2 | |
| SCHEMBL17674406 | 0.77 | TFPI2 (0.55) | CCR2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL2651525 | 0.76 | PIM1 (0.47) | PIM1PPARDPPARAKDM4EKMT2A | |
| SCHEMBL16619618 | 0.75 | CA2 (0.52) | PIM1PIM2CES2CCR2KRAS | |
| SCHEMBL4959132 | 0.74 | PRKCI (0.52) | CCR2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL2659180 | 0.74 | OXER1 (0.63) | PIM1CCR2OXER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9758453-B2 | One-component reagent for the fluoroalkylation reaction | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2017-09-12 | — | — | US | disclosed |
| US-20170066717-A1 | NEW PHENYLAZETIDINECARBOXYLATE OR -CARBOXAMIDE COMPOUNDS | INVENTIVA (FR) | 2017-03-09 | — | — | US | disclosed |
| US-20160185691-A1 | One-Component Reagent for the Fluoroalkylation Reaction | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF LLLINOIS (US) | 2016-06-30 | — | — | US | disclosed |
| US-9193648-B2 | Fluoroalkylation methods and reagents | BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2015-11-24 | — | — | US | disclosed |
| US-20130225815-A1 | Fluoroalkylation Methods And Reagents | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2013-08-29 | — | — | US | disclosed |
| EP-2606048-A1 | FLUOROALKYLATION METHODS AND REAGENTS | The Board of Trustees of the University of Illinois (US) | 2013-06-26 | — | — | EP | disclosed |
| WO-2012024564-A1 | FLUOROALKYLATION METHODS AND REAGENTS | THE BOARD OF TRUSTESS OF THE UNIVERSITY OF ILLINOIS (US) | 2012-02-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130225815-A1 | Fluoroalkylation Methods And Reagents | ALK, AFF4, AFF2 | PIM1 1415/4885PIM2 1176/4885CES2 744/4885 |
| US-20170066717-A1 | NEW PHENYLAZETIDINECARBOXYLATE OR -CARBOXAMIDE COMPOUNDS | NCOR1, NCOR2, NCOA1 | PIM1 1594/4885PIM2 2416/4885CES2 2319/4885 |
| US-20160185691-A1 | One-Component Reagent for the Fluoroalkylation Reaction | AOC1, AOC3, AOC2 | PIM1 4530/4885PIM2 4612/4885CES2 98/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.