Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 7/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.34 |
| ▸ | LPL | P06858 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29896800 | 0.83 | BACE1 (0.41) | ROCK1BACE1LIPGPRMT5WDR77 | |
| SCHEMBL15796518 | 0.83 | BACE1 (0.41) | ROCK1BACE1LIPGPRMT5WDR77 | |
| SCHEMBL18765483 | 0.83 | ALOX15 (0.43) | ROCK1BACE1ALOX15MAPTSMN1; SMN2 | |
| SCHEMBL18765486 | 0.83 | ALOX15 (0.43) | ROCK1BACE1ALOX15MAPTSMN1; SMN2 | |
| SCHEMBL28980408 | 0.80 | ITGB3 (0.37) | ITGB3ITGA2BROCK1BACE1PRMT5 | |
| SCHEMBL29896931 | 0.78 | KCNH2 (0.42) | ROCK1LIPGPRMT5WDR77LPL | |
| SCHEMBL15796700 | 0.78 | KCNH2 (0.42) | ROCK1LIPGPRMT5WDR77LPL | |
| SCHEMBL29421580 | 0.77 | GRM5 (0.47) | ROCK1BACE1LIPGPRMT5WDR77 | |
| SCHEMBL2041556 | 0.77 | GRM5 (0.47) | ROCK1BACE1LIPGPRMT5WDR77 | |
| SCHEMBL27157771 | 0.76 | BACE1 (0.38) | ROCK1BACE1LIPGPRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115925679-A | Biaryl derivatives as GPR120 agonists | 株式会社LG化学 | 2023-04-07 | — | — | CN | disclosed |