Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | GLS | O94925 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | CASP3 | P42574 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27655259 | 0.90 | SMN1; SMN2 (0.50) | CA12CA9KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL17044807 | 0.85 | ALDH1A1 (0.47) | CA12CA9KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL16465525 | 0.85 | ALDH1A1 (0.47) | CA12CA9KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL22121427 | 0.84 | GLS (0.59) | SMN1; SMN2GLSCASP3RAB9ANPC1 | |
| SCHEMBL10713815 | 0.83 | CA12 (0.55) | CA12CA9KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL10713825 | 0.83 | CA12 (0.55) | CA12CA9KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL11465897 | 0.83 | GLS (0.47) | CA12CA9KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL19510895 | 0.79 | MEN1 (0.53) | KMT2AMEN1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL30350633 | 0.79 | MEN1 (0.53) | KMT2AMEN1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL5839070 | 0.77 | GLS (0.52) | SMN1; SMN2GLSCASP3RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107567443-B | Biaryl derivatives as GPR120 agonists | 株式会社LG化学 | 2023-04-28 | — | — | CN | disclosed |
| CN-115925679-A | Biaryl derivatives as GPR120 agonists | 株式会社LG化学 | 2023-04-07 | — | — | CN | disclosed |