Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | GLS | O94925 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16465525 | 1.00 | ALDH1A1 (0.47) | ALDH1A1CA12CA9GLSKMT2A | |
| SCHEMBL28980452 | 0.85 | CA12 (0.51) | ALDH1A1CA12CA9GLSKMT2A | |
| SCHEMBL16654972 | 0.83 | ALDH1A1 (0.50) | ALDH1A1CA12CA9HPGD | |
| SCHEMBL16654973 | 0.83 | ALDH1A1 (0.50) | ALDH1A1CA12CA9HPGD | |
| SCHEMBL22121427 | 0.82 | GLS (0.59) | GLSSMN1; SMN2 | |
| SCHEMBL11465897 | 0.81 | GLS (0.47) | ALDH1A1CA12CA9GLSKMT2A | |
| SCHEMBL30350633 | 0.81 | MEN1 (0.53) | ALDH1A1KMT2AMEN1SMN1; SMN2GAA | |
| SCHEMBL19510895 | 0.81 | MEN1 (0.53) | ALDH1A1KMT2AMEN1SMN1; SMN2GAA | |
| SCHEMBL21686720 | 0.80 | GLS (0.52) | GLSKMT2AMEN1HPGD | |
| SCHEMBL9207150 | 0.79 | GLS (0.55) | GLSKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2888268-B1 | NOVEL SPIROOXINDOLE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | OKINAWA INST SCIENCE & TECH SCHOOL CORP (JP) | 2018-08-22 | — | — | EP | disclosed |
| US-9309261-B2 | Spirooxindole derivative and process for producing the same | OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION (JP) | 2016-04-12 | — | — | US | disclosed |
| US-20150246927-A1 | NOVEL SPIROOXINDOLE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION (JP) | 2015-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150246927-A1 | NOVEL SPIROOXINDOLE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | CCNA1, REN, AKR1D1 | ALDH1A1 256/4885CA12 4767/4885CA9 4127/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.