Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.43 |
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 6/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21952079 | 0.84 | NPSR1 (0.52) | HPGDKMT2AMEN1ALDH1A1MAPK1 | |
| SCHEMBL28678930 | 0.83 | HPGD (0.50) | HPGDKMT2AMEN1ALDH1A1MAPK1 | |
| SCHEMBL28676728 | 0.82 | HPGD (0.53) | HPGDKMT2AMEN1ALDH1A1MAPK1 | |
| SCHEMBL21952083 | 0.77 | HPGD (0.52) | HPGDKMT2AMEN1ALDH1A1MAPK1 | |
| SCHEMBL24209687 | 0.76 | KDM4E (0.48) | KMT2AMEN1ALDH1A1MAPK1POLB | |
| SCHEMBL28681663 | 0.74 | HPGD (0.56) | HPGDKMT2AMEN1ALDH1A1MAPK1 | |
| SCHEMBL21952064 | 0.74 | MAPT (0.60) | HPGDKMT2AMEN1ALDH1A1MAPK1 | |
| SCHEMBL28655780 | 0.73 | MAPK1 (0.56) | HPGDKMT2AMEN1ALDH1A1MAPK1 | |
| SCHEMBL28660619 | 0.72 | HPGD (0.53) | HPGDKMT2AMEN1ALDH1A1MAPK1 | |
| SCHEMBL28660616 | 0.71 | HPGD (0.46) | HPGDKMT2AMEN1ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115768422-A | Ubiquitin ligase inhibitors for the treatment of cancer | 诺沃亚桑托斯教授基金会 | 2023-03-07 | — | — | CN | disclosed |