Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 7/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 4/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | ALPL | P05186 | 3/20 | 0.38 |
| ▸ | ALPG | P10696 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28673832 | 0.88 | MEN1 (0.53) | HPGDMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL28669727 | 0.88 | MEN1 (0.48) | HPGDMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL28659024 | 0.88 | ALDH1A1 (0.48) | HPGDMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL28664789 | 0.85 | HPGD (0.45) | HPGDMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL28655707 | 0.85 | ALDH1A1 (0.51) | HPGDMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL21952032 | 0.82 | TSHR (0.63) | HPGDMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL21952036 | 0.77 | TSHR (0.42) | HPGDMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL28678930 | 0.75 | HPGD (0.50) | HPGDMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL21952064 | 0.73 | MAPT (0.60) | HPGDMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL28676728 | 0.73 | HPGD (0.53) | HPGDMEN1KMT2AALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115768422-A | Ubiquitin ligase inhibitors for the treatment of cancer | 诺沃亚桑托斯教授基金会 | 2023-03-07 | — | — | CN | disclosed |
| CN-113677340-A | Compounds that selectively and efficiently inhibit Hakai-mediated ubiquitination as anti-cancer agents | 诺沃亚桑托斯教授基金会 | 2021-11-19 | — | — | CN | disclosed |