Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.46 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.46 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30804513 | 1.00 | LTA4H (0.50) | LTA4HSMN1; SMN2GNAI3GNAO1GNAI1 | |
| SCHEMBL19488417 | 0.90 | SMN1; SMN2 (0.53) | SMN1; SMN2GNAI3GNAO1GNAI1TP53 | |
| SCHEMBL3277644 | 0.85 | LTA4H (0.51) | LTA4HSMN1; SMN2BRD4TP53GAA | |
| SCHEMBL13146450 | 0.85 | LTA4H (0.51) | LTA4HSMN1; SMN2BRD4TP53GAA | |
| SCHEMBL28953619 | 0.84 | LTA4H (0.48) | LTA4HSMN1; SMN2BRD4TP53GAA | |
| SCHEMBL17915383 | 0.83 | LTA4H (0.50) | LTA4HSMN1; SMN2BRD4TP53GAA | |
| SCHEMBL16418027 | 0.83 | LTA4H (0.56) | LTA4HSMN1; SMN2BRD4TP53GAA | |
| SCHEMBL8518749 | 0.82 | BCHE (0.50) | LTA4HSMN1; SMN2GNAI3GNAO1GNAI1 | |
| SCHEMBL23375191 | 0.81 | SMN1; SMN2 (0.52) | LTA4HSMN1; SMN2TP53GAAALDH1A1 | |
| SCHEMBL16556615 | 0.81 | SMN1; SMN2 (0.52) | LTA4HSMN1; SMN2TP53GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115916784-A | Novel imidazopyrazine derivatives | 豪夫迈·罗氏有限公司 | 2023-04-04 | — | — | CN | disclosed |