Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 7/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | THRA | P10827 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | DRD5 | P21918 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.42 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.42 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19637430 | 0.91 | LTA4H (0.54) | BCHELTA4HTHRATHRBGAA | |
| SCHEMBL13472645 | 0.90 | THRA (0.56) | BCHETHRATHRBGAAKCNH2 | |
| SCHEMBL13146450 | 0.90 | LTA4H (0.51) | BCHELTA4HTHRATHRBGAA | |
| SCHEMBL9921239 | 0.86 | LTA4H (0.51) | BCHELTA4HTHRATHRBGAA | |
| SCHEMBL28953619 | 0.86 | LTA4H (0.48) | BCHELTA4HTHRATHRBGAA | |
| SCHEMBL3277644 | 0.83 | LTA4H (0.51) | LTA4HTHRATHRBGAABRD4 | |
| SCHEMBL18914467 | 0.83 | LTA4H (0.46) | BCHELTA4HTHRATHRBGAA | |
| SCHEMBL23375191 | 0.83 | SMN1; SMN2 (0.52) | LTA4HTHRATHRBGAATP53 | |
| SCHEMBL16556615 | 0.83 | SMN1; SMN2 (0.52) | LTA4HTHRATHRBGAATP53 | |
| SCHEMBL22675502 | 0.83 | SMN1; SMN2 (0.52) | LTA4HTHRATHRBGAATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0748310-B1 | DIESTERS OF CARBONIC ACID ENDOWED WITH ANTIVIRAL AND ANTI-INFLAMMATORY ACTIVITY | ITALFARMACO SPA (IT) | 1999-06-02 | — | — | EP | disclosed |
| US-5827881-A | ADMINISTERING FOR TREATMENT OF VIRAL DISEASES OR AS ANTIINFLAMMATORY AGENTS | ITALFARMACO S.P.A. (IT) | 1998-10-27 | — | — | US | disclosed |