Diphenylsulfane

Diphenylsulfane

SCHEMBL2898246

O=S(=O)(Oc1ccc(Sc2ccccc2)cc1)c1ccc(C(F)(F)F)cc1.c1ccc(Sc2ccccc2)cc1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ENPP3 O14638 6/20 0.50
ENPP1 P22413 5/20 0.50
ENPP2 Q13822 4/20 0.48
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CA9 Q16790 1/20 0.47
TDP1 Q9NUW8 3/20 0.46
KIF11 P52732 1/20 0.44
STS P08842 1/20 0.42
AR P10275 1/20 0.41
MAPT P10636 2/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
L3MBTL1 Q9Y468 2/20 0.40
MEN1 O00255 1/20 0.39
ALDH1A1 P00352 1/20 0.39
RECQL P46063 1/20 0.39
KMT2A Q03164 1/20 0.39
LMNA P02545 1/20 0.38
HTT P42858 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diphenylsulfane SCHEMBL2898459 0.92 ENPP3 (0.49) ENPP3ENPP1ENPP2CA1CA2
Diphenylsulfane SCHEMBL4864595 0.92 MEN1 (0.50) ENPP3ENPP1ENPP2CA1CA2
Diphenylsulfane SCHEMBL2902271 0.90 ENPP3 (0.45) ENPP3ENPP1ENPP2CA1CA2
SCHEMBL2569898 0.87 TDP1 (0.42) ENPP3ENPP1ENPP2CA1CA2
SCHEMBL15453538 0.86 TDP1 (0.61) ENPP3ENPP1ENPP2CA1CA2
SCHEMBL27621077 0.86 ENPP3 (0.54) ENPP3ENPP1ENPP2CA1CA2
Methane SCHEMBL3963790 0.86 TDP1 (0.41) ENPP3ENPP1ENPP2CA1CA2
Diphenylsulfane SCHEMBL2903351 0.85 TDP1 (0.62) ENPP3ENPP1ENPP2CA2TDP1
SCHEMBL9309266 0.83 TDP1 (0.65) ENPP3ENPP1ENPP2CA2TDP1
Diphenylsulfane SCHEMBL2895786 0.81 MAPT (0.52) ENPP3ENPP1ENPP2CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1253470-B1 Radiation-sensitive resin composition JSR CORP (JP) 2010-06-16 EP disclosed
EP-1270553-B1 Acid generator, sulfonic acid, sulfonic acid derivatives and radiation-sensitive resin composition JSR CORP (JP) 2009-11-18 EP disclosed
US-6846607-B2 Carbazole derivative and chemically amplified radiation-sensitive resin composition JSR CORPORATION (JP) 2005-01-25 US disclosed
US-6770780-B1 QUATERNIZATION OF T-BUTYL BROMOACETATE WITH TRI(N-BUTYL)PHOSPHINE TO FORM PHOSPHONIUM SALT; REACTING WITH BASE TO FORM PHOSPHORUS YLIDE; FORMING 2,4,6-TRIS(3', 5'-DI-T-BUTYL-4'-HYDROXYBENZYL)METHYL-STYRENE; HYDROLYSIS JSR CORPORATION (JP) 2004-08-03 US disclosed
EP-1343048-A2 Anthracene derivative and radiation-sensitive resin composition JSR Corporation (JP) 2003-09-10 EP disclosed
EP-1270553-A2 Acid generator, sulfonic acid, sulfonic acid derivatives and radiation-sensitive resin composition JSR Corporation (JP) 2003-01-02 EP disclosed
EP-1253470-A2 Radiation-sensitive resin composition JSR Corporation (JP) 2002-10-30 EP disclosed
EP-1231205-A1 VINYLPHENYLPROPIONIC ACID DERIVATIVES, PROCESSES FOR PRODUCTION OF THE DERIVATIVES, POLYMERS THEREOF AND RADIOSENSITIVE RESIN COMPOSITIONS JSR Corporation (JP) 2002-08-14 EP disclosed