Diphenylsulfane

Diphenylsulfane

SCHEMBL4864595

CC(C)(C)c1ccc(OS(=O)(=O)c2ccc(C(F)(F)F)cc2)cc1.c1ccc(Sc2ccccc2)cc1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.50
ALDH1A1 P00352 1/20 0.50
MAPT P10636 1/20 0.50
RECQL P46063 1/20 0.50
KMT2A Q03164 1/20 0.50
HSD11B1 P28845 1/20 0.48
HSD17B3 P37058 1/20 0.48
ENPP1 P22413 10/20 0.47
ENPP3 O14638 10/20 0.47
ENPP2 Q13822 5/20 0.45
KDM4E B2RXH2 1/20 0.44
KDM4A O75164 1/20 0.44
CA1 P00915 2/20 0.43
CA2 P00918 2/20 0.43
CA9 Q16790 2/20 0.43
APEX1 P27695 1/20 0.43
TDP1 Q9NUW8 1/20 0.42
KIF11 P52732 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diphenylsulfane SCHEMBL2898246 0.92 ENPP3 (0.50) MEN1ALDH1A1MAPTRECQLKMT2A
Diphenylsulfane SCHEMBL2895786 0.91 MAPT (0.52) MEN1ALDH1A1MAPTRECQLKMT2A
Diphenylsulfane SCHEMBL2902271 0.90 ENPP3 (0.45) MEN1ALDH1A1MAPTRECQLKMT2A
Diphenylsulfane SCHEMBL2191898 0.88 ALDH1A1 (0.51) MEN1ALDH1A1MAPTRECQLKMT2A
Diphenylsulfane SCHEMBL2898459 0.87 ENPP3 (0.49) MEN1ALDH1A1MAPTRECQLKMT2A
Diphenylsulfane SCHEMBL2191112 0.84 CA1 (0.50) MEN1ALDH1A1MAPTRECQLKMT2A
Diphenylsulfane SCHEMBL4423381 0.84 CA1 (0.42) MEN1ALDH1A1MAPTRECQLKMT2A
SCHEMBL8393963 0.82 HSD11B1 (0.62) MEN1ALDH1A1MAPTRECQLKMT2A
SCHEMBL15453538 0.82 TDP1 (0.61) ALDH1A1MAPTHSD11B1ENPP1ENPP3
SCHEMBL2986520 0.82 TDP1 (0.61) MEN1ALDH1A1MAPTRECQLKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7314701-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2008-01-01 US disclosed
US-6933094-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2005-08-23 US disclosed
US-20050095527-A1 Radiation-sensitive resin composition JSR CORPORATION (JP) 2005-05-05 US disclosed
US-6824954-B2 DIHALOMETHYL SULFONYLOXIME COMPOUNDS; FOR EXAMPLE, 2,2-DIFLUORO-2-METHYLACETOPHENONE-O-METHYLSULFONYLOXIME; HEAT STABILITY AND STORAGE STABILITY; SENSITIVE TO FAR ULTRAVIOLET RADIATION OR ELECTRON BEAMS; RESISTS JSR CORPORATION (JP) 2004-11-30 US disclosed
US-6770780-B1 QUATERNIZATION OF T-BUTYL BROMOACETATE WITH TRI(N-BUTYL)PHOSPHINE TO FORM PHOSPHONIUM SALT; REACTING WITH BASE TO FORM PHOSPHORUS YLIDE; FORMING 2,4,6-TRIS(3', 5'-DI-T-BUTYL-4'-HYDROXYBENZYL)METHYL-STYRENE; HYDROLYSIS JSR CORPORATION (JP) 2004-08-03 US disclosed
US-20030113660-A1 Sulfonyloxime compound, and radiation sensitive acid generator, positive type radiation sensitive resin composition and negative type radiation sensitive resin composition using same JSR CORPORATION (JP) 2003-06-19 US disclosed
US-6506537-B2 Photopolymerization JSR CORPORATION (JP) 2003-01-14 US disclosed
EP-1231205-A1 VINYLPHENYLPROPIONIC ACID DERIVATIVES, PROCESSES FOR PRODUCTION OF THE DERIVATIVES, POLYMERS THEREOF AND RADIOSENSITIVE RESIN COMPOSITIONS JSR Corporation (JP) 2002-08-14 EP disclosed
US-20020058201-A1 Radiation-sensitive resin composition JSR CORPORATION (JP) 2002-05-16 US disclosed
EP-1193558-A2 Radiation-sensitive resin composition JSR Corporation (JP) 2002-04-03 EP disclosed
US-20020012872-A1 Radiation-sensitive resin composition JSR CORPORATION (JP) 2002-01-31 US disclosed
EP-1164433-A1 Radiation-sensitive resin composition JSR Corporation (JP) 2001-12-19 EP disclosed