SCHEMBL2898371

SCHEMBL2898371

NC(=O)CCC1CN(c2cc(F)cc(F)c2)C(=O)O1

nearest known ligand 0.48

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
GRM2 Q14416 16/20 0.48
MAOA P21397 2/20 0.44
CALML3 P27482 1/20 0.40
MAOB P27338 1/20 0.40
F10 P00742 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6644912 0.88 GRM2 (0.65) GRM2MAOACALML3MAOB
SCHEMBL2891483 0.86 MAOA (0.46) GRM2MAOACALML3MAOBF10
SCHEMBL6686605 0.83 F10 (0.57) GRM2MAOACALML3MAOBF10
SCHEMBL27576680 0.82 GRM2 (0.70) GRM2MAOAMAOB
SCHEMBL5763614 0.81 CALML3 (0.47) GRM2MAOACALML3MAOBF10
SCHEMBL2890876 0.81 CALML3 (0.47) GRM2MAOACALML3MAOBF10
SCHEMBL28248008 0.81 GRM2 (0.46) GRM2MAOACALML3MAOBF10
SCHEMBL6635972 0.81 MAOA (0.42) GRM2MAOACALML3MAOBF10
SCHEMBL30762654 0.81 MAOA (0.54) GRM2MAOACALML3MAOBF10
SCHEMBL2896810 0.80 F10 (0.52) GRM2MAOACALML3MAOBF10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100286211-A1 OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS RANBAXY LABORATORIES LIMITED (IN) 2010-11-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100286211-A1 OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS OXA1L, PDK4, MLYCD GRM2 3646/4885MAOA 1717/4885CALML3 3047/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.