Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 13/20 | 0.57 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CLPP | Q16740 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28984477 | 0.93 | ENPP2 (0.61) | ENPP2PTGDR2 | |
| SCHEMBL28984505 | 0.91 | ENPP2 (0.58) | ENPP2TP53 | |
| SCHEMBL28984491 | 0.91 | ENPP2 (0.52) | ENPP2CLPP | |
| SCHEMBL28984474 | 0.91 | ENPP2 (0.52) | ENPP2PTGDR2 | |
| SCHEMBL28984486 | 0.91 | ENPP2 (0.52) | ENPP2PTGDR2 | |
| SCHEMBL28984516 | 0.91 | ENPP2 (0.54) | ENPP2PTGDR2 | |
| SCHEMBL28984482 | 0.90 | PTGDR2 (0.52) | ENPP2PTGDR2TP53CLPP | |
| SCHEMBL28984535 | 0.88 | PTGDR2 (0.53) | ENPP2PTGDR2TP53THRBALDH1A1 | |
| SCHEMBL28984498 | 0.88 | ENPP2 (0.55) | ENPP2PTGDR2CLPP | |
| SCHEMBL28984507 | 0.87 | ENPP2 (0.52) | ENPP2PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115611896-A | Compound containing tetralone or tetrahydropyridopyrimidone skeleton and preparation method and pharmaceutical application thereof | 中国药科大学 | 2023-01-17 | — | — | CN | disclosed |