Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 13/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28984477 | 0.92 | ENPP2 (0.61) | ENPP2CNR2CNR1 | |
| SCHEMBL28984499 | 0.91 | ENPP2 (0.57) | ENPP2TP53 | |
| SCHEMBL28984486 | 0.90 | ENPP2 (0.52) | ENPP2 | |
| SCHEMBL28984491 | 0.90 | ENPP2 (0.52) | ENPP2 | |
| SCHEMBL28984474 | 0.90 | ENPP2 (0.52) | ENPP2 | |
| SCHEMBL28984516 | 0.90 | ENPP2 (0.54) | ENPP2 | |
| SCHEMBL28984498 | 0.89 | ENPP2 (0.55) | ENPP2 | |
| SCHEMBL28984478 | 0.89 | ENPP2 (0.63) | ENPP2MAPT | |
| SCHEMBL28984535 | 0.87 | PTGDR2 (0.53) | ENPP2TP53MAPT | |
| SCHEMBL24914406 | 0.87 | CLPP (0.60) | ENPP2TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115611896-A | Compound containing tetralone or tetrahydropyridopyrimidone skeleton and preparation method and pharmaceutical application thereof | 中国药科大学 | 2023-01-17 | — | — | CN | disclosed |