Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 17/20 | 0.61 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28984516 | 0.94 | ENPP2 (0.54) | ENPP2PTGDR2 | |
| SCHEMBL28984499 | 0.93 | ENPP2 (0.57) | ENPP2PTGDR2 | |
| SCHEMBL28984505 | 0.92 | ENPP2 (0.58) | ENPP2CNR1CNR2 | |
| SCHEMBL28984486 | 0.92 | ENPP2 (0.52) | ENPP2MEN1KMT2APTGDR2 | |
| SCHEMBL28984474 | 0.92 | ENPP2 (0.52) | ENPP2MEN1KMT2APTGDR2 | |
| SCHEMBL28984507 | 0.92 | ENPP2 (0.52) | ENPP2PTGDR2 | |
| SCHEMBL28984491 | 0.92 | ENPP2 (0.52) | ENPP2 | |
| SCHEMBL28984482 | 0.91 | PTGDR2 (0.52) | ENPP2PTGDR2 | |
| SCHEMBL28984527 | 0.89 | ENPP2 (0.49) | ENPP2CNR2PTGDR2 | |
| SCHEMBL28984498 | 0.89 | ENPP2 (0.55) | ENPP2PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115611896-A | Compound containing tetralone or tetrahydropyridopyrimidone skeleton and preparation method and pharmaceutical application thereof | 中国药科大学 | 2023-01-17 | — | — | CN | disclosed |