Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 16/20 | 0.49 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28984477 | 0.89 | ENPP2 (0.61) | ENPP2PTGDR2CNR2 | |
| SCHEMBL28984480 | 0.87 | ENPP2 (0.46) | ENPP2 | |
| SCHEMBL28984496 | 0.86 | ENPP2 (0.48) | ENPP2PTGDR2KDM4EALDH1A1 | |
| SCHEMBL30130300 | 0.86 | DDB1 (0.51) | ENPP2PTGDR2 | |
| SCHEMBL24914526 | 0.85 | DDB1 (0.50) | ENPP2PTGDR2 | |
| SCHEMBL30130131 | 0.85 | DDB1 (0.50) | ENPP2PTGDR2 | |
| SCHEMBL28984516 | 0.85 | ENPP2 (0.54) | ENPP2PTGDR2 | |
| SCHEMBL28984494 | 0.85 | THRB (0.48) | ENPP2PTGDR2 | |
| SCHEMBL28984483 | 0.85 | MAPT (0.50) | ENPP2ALDH1A1 | |
| SCHEMBL28984490 | 0.85 | PTGDR2 (0.51) | ENPP2PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115611896-A | Compound containing tetralone or tetrahydropyridopyrimidone skeleton and preparation method and pharmaceutical application thereof | 中国药科大学 | 2023-01-17 | — | — | CN | disclosed |