Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | ACHE | P22303 | 7/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.41 |
| ▸ | BCHE | P06276 | 5/20 | 0.40 |
| ▸ | CHRNE | Q04844 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8781758 | 0.80 | KDM4E (0.50) | KDM4EACHEBCHECHRNEHSD17B10 | |
| SCHEMBL10871024 | 0.80 | KDM4E (0.50) | KDM4EACHEGRIN1GRIN2ABCHE | |
| SCHEMBL28984981 | 0.78 | KDM4E (0.53) | KDM4EACHEGRIN1GRIN2ABCHE | |
| SCHEMBL4495989 | 0.77 | KDM4E (0.82) | KDM4EACHEGRIN1GRIN2ABCHE | |
| SCHEMBL30411626 | 0.77 | ACHE (0.70) | KDM4EACHEGRIN1GRIN2ABCHE | |
| Hydrochloric Acid SCHEMBL8984092 | 0.75 | KDM4E (0.80) | KDM4EACHEGRIN1GRIN2ABCHE | |
| SCHEMBL2655216 | 0.73 | HRH4 (0.42) | KDM4EACHECHRNEHSD17B10ALDH1A1 | |
| SCHEMBL28984980 | 0.72 | ACHE (0.66) | KDM4EACHEGRIN1GRIN2ABCHE | |
| SCHEMBL28984972 | 0.72 | ACHE (0.62) | KDM4EACHEGRIN1GRIN2ABCHE | |
| SCHEMBL2660900 | 0.71 | PARP1 (0.38) | KDM4EACHEALDH1A1HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115947686-B | 9-Amino-3, 4-dihydro-acridine-1 (2H) -ketone compound and application thereof | 浙江工业大学 | 2024-11-12 | — | — | CN | disclosed |
| CN-115947686-A | 9-amino-3, 4-dihydroacridine-1 (2H) -ketone compound and application thereof | 浙江工业大学 | 2023-04-11 | — | — | CN | disclosed |