Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TNKS | O95271 | 5/20 | 0.43 |
| ▸ | TNKS2 | Q9H2K2 | 5/20 | 0.43 |
| ▸ | PARP1 | P09874 | 3/20 | 0.43 |
| ▸ | ACHE | P22303 | 4/20 | 0.42 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.39 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28984974 | 0.81 | ACHE (0.66) | KDM4EALDH1A1MAPTNPSR1ACHE | |
| SCHEMBL28984969 | 0.80 | KDM4E (0.53) | KDM4EALDH1A1MAPTNPSR1ACHE | |
| SCHEMBL8781758 | 0.80 | KDM4E (0.50) | KDM4EALDH1A1MAPTPARP1ACHE | |
| SCHEMBL12043413 | 0.79 | ACHE (0.65) | KDM4EALDH1A1ACHEBCHEGRIN1 | |
| SCHEMBL4495989 | 0.74 | KDM4E (0.82) | KDM4EALDH1A1ACHEBCHEGRIN1 | |
| SCHEMBL23537370 | 0.72 | ALDH1A1 (0.49) | KDM4EALDH1A1MAPTNPSR1ACHE | |
| Hydrochloric Acid SCHEMBL8984092 | 0.72 | KDM4E (0.80) | KDM4EALDH1A1MAPTACHEBCHE | |
| SCHEMBL29824468 | 0.72 | ALDH1A1 (0.49) | KDM4EALDH1A1MAPTNPSR1ACHE | |
| SCHEMBL8785150 | 0.72 | ACHE (0.64) | KDM4EALDH1A1MAPTACHEBCHE | |
| SCHEMBL10848798 | 0.72 | ACHE (0.67) | KDM4EALDH1A1MAPTACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115947686-B | 9-Amino-3, 4-dihydro-acridine-1 (2H) -ketone compound and application thereof | 浙江工业大学 | 2024-11-12 | — | — | CN | disclosed |
| CN-115947686-A | 9-amino-3, 4-dihydroacridine-1 (2H) -ketone compound and application thereof | 浙江工业大学 | 2023-04-11 | — | — | CN | disclosed |
| EP-0179383-A2 | 9-Amino-1,2,3,4-tetrahydroacridin-1-ol and related compounds, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1986-04-30 | — | — | EP | disclosed |