SCHEMBL2898503

SCHEMBL2898503

NCCN(c1cccc2ccccc12)c1cccc2ccccc12

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 6/20 0.44
HTR1B P28222 3/20 0.43
CA12 O43570 1/20 0.43
CA3 P07451 1/20 0.43
CA4 P22748 1/20 0.43
CA6 P23280 1/20 0.43
CA5A P35218 1/20 0.43
CA7 P43166 1/20 0.43
CA9 Q16790 1/20 0.43
CA14 Q9ULX7 1/20 0.43
CA5B Q9Y2D0 1/20 0.43
ALDH1A1 P00352 5/20 0.42
TSHR P16473 3/20 0.42
HSD17B10 Q99714 3/20 0.42
RECQL P46063 1/20 0.42
CYP3A4 P08684 1/20 0.40
HPGD P15428 1/20 0.40
KEAP1 Q14145 1/20 0.40
CYP1A2 P05177 1/20 0.37
CYP2D6 P10635 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1593235 0.82 SIGMAR1 (0.43) SIGMAR1HTR1BCA12CA3CA4
SCHEMBL5931116 0.81 SIGMAR1 (0.50) SIGMAR1HTR1BCA12CA3CA4
SCHEMBL3132043 0.81 SIGMAR1 (0.42) SIGMAR1HTR1BCA12CA3CA4
SCHEMBL11705046 0.80 SIGMAR1 (0.44) SIGMAR1HTR1BALDH1A1TSHRHSD17B10
Hydrochloric Acid SCHEMBL5679371 0.79 SIGMAR1 (0.49) SIGMAR1HTR1BCA12CA3CA4
SCHEMBL10401416 0.75 MMP9 (0.47) SIGMAR1HTR1BALDH1A1TSHRTDP1
SCHEMBL7962443 0.75 SIGMAR1 (0.47) SIGMAR1ALDH1A1TSHRHSD17B10CYP3A4
SCHEMBL14461587 0.75 SIGMAR1 (0.54) SIGMAR1ALDH1A1TSHRHSD17B10CYP1A2
SCHEMBL28985641 0.72 CARM1 (0.41) SIGMAR1ALDH1A1TSHRHSD17B10CYP3A4
Hydrochloric Acid SCHEMBL3722949 0.72 MMP9 (0.50) SIGMAR1ALDH1A1TSHRHSD17B10RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2215101-A1 CATIONIC TRANSITION METAL CATALYSTS Kanata Chemical Technologies Inc. (CA) 2010-08-11 EP claimed
WO-2009055912-A1 CATIONIC TRANSITION METAL CATALYSTS KANATA CHEMICAL TECHNOLOGIES INC. (CA) 2009-05-07 WO claimed
CN-114478242-B Salen-Ti complex catalyst and method for catalyzing asymmetric hydrogen atom transfer reaction by using same 山东大学 2023-04-04 CN disclosed
CN-114478242-A Salen-Ti complex catalyst and method for catalyzing asymmetric hydrogen atom transfer reaction by using same 山东大学 2022-05-13 CN disclosed
US-4315031-A Thiosubstituted amino acids SCIENCE UNION ET CIE (FR) 1982-02-09 US disclosed
US-4283407-A ANTIHYPERTENSIVE AGENTS SCIENCE UNION ET CIE (FR) 1981-08-11 US disclosed